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Principen vs. Augmentin

Reviewed on 1/24/2019

Are Principen and Augmentin the Same Thing?

Principen (ampicillin) and Augmentin (amoxicillin/clavulanate) are penicillin-type antibiotics used to treat many different types of infections caused by bacteria.

Principen is a penicillin-type antibiotic.

Side effects of Principen and Augmentin that are similar include nausea, vomiting, stomach pain, diarrhea, vaginal itching or discharge, headache, or oral thrush (white patches inside your mouth or throat).

Side effects of Principen that are different from Augmentin include mouth/tongue sores or swollen, black, or "hairy" tongue.

Side effects of Augmentin that are different from Principen include gas, skin rash, or itching.

What Are Possible Side Effects of Principen?

Common side effects of Principen include:

  • nausea,
  • vomiting,
  • stomach pain,
  • diarrhea,
  • vaginal itching or discharge,
  • headache,
  • mouth/tongue sores,
  • thrush (white patches inside your mouth or throat), or
  • swollen, black, or "hairy" tongue.

Tell your doctor if you have rare but very serious side effects of Principen including:

  • dark urine,
  • persistent nausea or vomiting,
  • yellowing eyes or skin,
  • easy bruising or bleeding, or
  • persistent sore throat or fever.

What Are Possible Side Effects of Augmentin?

Common side effects of Augmentin include:

  • Nausea
  • Vomiting
  • Headache
  • Diarrhea
  • Gas
  • Stomach pain
  • Skin rash or itching
  • White patches in your mouth or throat
  • Vaginal yeast infection (itching or discharge)

Rare and severe side effects of Augmentin can include:

  • watery or bloody diarrhea;
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;
  • easy bruising or bleeding;
  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
  • agitation, confusion, unusual thoughts or behavior, seizures (convulsions);
  • nausea, upper stomach pain, itching, loss of appetite, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.  

What Is Principen?

Principen (ampicillin) is a penicillin-type antibiotic used to treat many different types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. Principen is available in generic form.

What Is Augmentin?

Augmentin (amoxicillin/clavulanate) is a combination antibiotic used to treat bacterial infections including sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.

QUESTION

Bowel regularity means a bowel movement every day. See Answer

What Drugs Interact With Principen?

Principen may interact with allopurinol, methotrexate, sulfa drugs, or tetracycline antibiotics. Tell your doctor all medications you are taking. Principen should be used only when prescribed during pregnancy. This medication passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Augmentin?

Augmentin may interact with allopurinol.

Augmentin may also interact with probenecid or blood thinners.

Augmentin is not expected to be harmful to an unborn baby, but a woman should tell her doctor if she is pregnant or plans to become pregnant during treatment. Amoxicillin and clavulanate potassium can pass into breast milk and may harm a nursing baby. Do not use Augmentin without telling your doctor if you are breastfeeding a baby.

How Should Principen Be Taken?

The usual oral dose range of Principen for most infections is 250 to 500 mg 4 times daily for 7-14 days. To treat gonorrhea, a single 3.5 g dose is administered along with probenecid.

How Should Augmentin Be Taken?

The dosage of Augmentin varies by the patient and the condition being treated.

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All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

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You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
SOURCE:

DailyMed. Principen (ampicillin) Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=da8da9c0-fa46-40d3-82c6-1a18ffa1b585

FDA. Augmentin Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050575s037550597s044050725s025050726s019lbl.pdf
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