Pristiq vs. Drizalma Sprinkle

Are Pristiq and Drizalma Sprinkle the Same Thing?

Pristiq (desvenlafaxine) and Drizalma Sprinkle (duloxetine delayed-release capsules) are serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants indicated for major depressive disorder.

Drizalma Sprinkle is also used to treat generalized anxiety disorder in adults and pediatric patients ages 7 years to 17 years old, diabetic peripheral neuropathic pain in adults, and chronic musculoskeletal pain in adults.

Side effects of Pristiq (desvenlafaxine) and Drizalma Sprinkle that are similar include nausea, dry mouth, drowsiness, constipation, decreased appetite, and increased sweating.

Side effects of Drizalma Sprinkle that are different from Pristiq include dizziness, sleep problems (insomnia), tightness in your jaw, weight loss, blurred vision, nervousness, decreased sex drive, impotence, and difficulty having an orgasm.

Both Pristiq and Drizalma Sprinkle may interact with alcohol, migraine headache medications, other antidepressants, narcotic pain medicines, lithium, tramadol, tryptophan, St. John's wort, blood thinners, nonsteroidal anti-inflammatory drugs (NSAIDs), and aspirin.

Pristiq may also interact with other medicines that make you sleepy (such as cold or allergy medicines, sedatives, sleeping pills, muscle relaxers, and medicines for seizures or anxiety), diuretics (water pills), linezolid, metoclopramide, midazolam, antibiotics, antifungals, heart or blood pressure medications, and HIV/AIDS medicines.

Drizalma Sprinkle may also interact with monoamine oxidase inhibitors (MAOIs), buspirone, amphetamines, cimetidine, ciprofloxacin, enoxacin, quinidine, phenothiazines, type 1C antiarrhythmics, aluminum-and magnesium-containing antacids, famotidine, proton pump inhibitors (PPIs), theophylline, caffeine, centrally acting CNS drugs, and highly plasma protein binding drugs.

What Are Possible Side Effects of Pristiq?

Common side effects of Pristiq include:

  • increased or excessive sweating,
  • dizziness,
  • drowsiness,
  • dry mouth,
  • constipation,
  • sleep problems (insomnia),
  • loss of appetite,
  • tightness in your jaw,
  • nausea,
  • weight loss,
  • blurred vision,
  • nervousness,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

What Are Possible Side Effects of Drizalma Sprinkle?

Common side effects of Drizalma Sprinkle include:

  • nausea,
  • dry mouth,
  • drowsiness,
  • constipation,
  • decreased appetite, and
  • increased sweating

What Is Pristiq?

Pristiq (desvenlafaxine) is type of antidepressant called a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder.

What Is Drizalma Sprinkle?

Drizalma Sprinkle (duloxetine delayed-release capsules) is a serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for major depressive disorder in adults, generalized anxiety disorder in adults and pediatric patients ages 7 years to 17 years old, diabetic peripheral neuropathic pain in adults, and chronic musculoskeletal pain in adults.

QUESTION

Depression is a(n) __________ . See Answer

What Drugs Interact With Pristiq?

Pristiq may interact with cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, medicines for seizures or anxiety, other antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, St. John's wort, tramadol, L-tryptophan, heart medications, or medicines to treat migraines.

Pristiq may also interact with diuretics (water pills), linezolid, lithium, metoclopramide, midazolam, antibiotics, antifungals, blood pressure medications, or HIV/AIDS medicines.

What Drugs Interact With Drizalma Sprinkle?

Drizalma Sprinkle may interact with monoamine oxidase inhibitors (MAOIs), triptans, tricyclic antidepressants, other SNRIs or SSRIs, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, St. John's wort, cimetidine, ciprofloxacin, enoxacin, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, warfarin, quinidine, phenothiazines, type 1C antiarrhythmics, aluminum-and magnesium-containing antacids, famotidine, proton pump inhibitors (PPIs), theophylline, caffeine, centrally acting CNS drugs, highly plasma protein binding drugs, and alcohol. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Drizalma Sprinkle; third trimester use may increase risk of symptoms of poor adaptation (respiratory distress, temperature instability, feeding difficulty, low muscle tone, tremor, irritability) in newborns. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy. Drizalma Sprinkle passes into breast milk but its effects on nursing infants are unknown. Consult your doctor before breastfeeding.

How Should Pristiq Be Taken?

The recommended dose for Pristiq is 50 mg once daily, with or without food.

How Should Drizalma Sprinkle Be Taken?

The dose of Drizalma Sprinkle is 60 mg daily for most conditions.

SLIDESHOW

Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow
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References


Pfizer. Pristiq Product Information.

https://www.pristiq.com/

FDA. Drizalma Sprinkle Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/212516s000lbl.pdf

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