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Protonix vs. Dexilant

Medical and Pharmacy Editor:

What Drugs Interact With Protonix?

Protonix may interact with atazanavir, blood thinners, digoxin, diuretics (water pills), ketoconazole, or methotrexate.

Protonix may also interact with nelfinavir, ampicillin, or iron.

What Drugs Interact With Dexilant?

Dexilant may interact with atazanavir, ampicillin, digoxin, iron, blood thinners such as warfarin, or ketoconazole.

Dexilant may also interact with digoxin, tacrolimus, or clopidogrel.

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How Should Protonix Be Taken?

The recommended adult dose of Protonix is 40 mg once daily.

  • Protonix Oral Suspension should be taken 30 minutes before a meal
  • Protonix Oral Suspension should only be taken with applesauce or apple juice 30 minutes before a meal.
  • Protonix Oral Suspension should not be taken in or with water or other liquids, or with other foods.
  • Protonix Oral Suspension should not be chewed or crushed.
  • Protonix Oral Suspension packet should not be divided to make a smaller dose.

How Should Dexilant Be Taken?

Taking Dexilant capsules with apples auce:

  1. Place 1 tablespoon of applesauce into a clean container.
  2. Carefully open the capsule and sprinkle the granules onto the applesauce.
  3. Swallow the applesauce and granules right away. Do not chew the granules. Do not save the applesauce and granules for later use.

Giving Dexilant capsules with water using an oral syringe:

  1. Place 20 mL of water into a clean container.
  2. Carefully open the capsule and empty the granules into the container of water.
  3. Use an oral syringe to draw up the water and granule mixture.
  4. Gently swirl the oral syringe to keep the granules from settling.
  5. Place the tip of the oral syringe in your mouth. Give the medicine right away. Do not save the water and granule mixture for later use.
  6. Refill the syringe with 10 mL of water and swirl gently. Place the tip of the oral syringe in your mouth and give the medicine that is left in the syringe.
  7. Repeat step 6.

Giving Dexilant capsules with water through a nasogastrictube (NG tube):

For people who have an NG tube that is size 16 French or larger, Dexilant may be given as follows:

  1. Place 20 mL of water into a clean container.
  2. Carefully open the capsule and empty the granules into the container of water.
  3. Use a 60 mL catheter-tip syringe to draw up the water and granule mixture.
  4. Gently swirl the catheter-tip syringe to keep the granules from settling.
  5. Connect the catheter-tip syringe to the NG tube.
  6. Give the mixture right away through the NG tube that goes into the stomach. Do not save the water and granule mixture for later use.
  7. Refill the catheter-tip syringe with 10 mL of water and swirl gently. Flush the NG tube with the water.
  8. Repeat step 7.
Reviewed on 2/7/2018


SOURCE:
RxList. Protonix Medication Guide.
https://www.rxlist.com/protonix-drug.htm#medguide
RxList. Dexilant Medication Guide.
https://www.rxlist.com/dexilant-drug.htm#medguide

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