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Protonix vs. Dexilant

Medical and Pharmacy Editor:

Are Protonix and Dexilant the Same Thing?

Protonix (pantoprazole sodium) and Dexilant (dexlansoprazole) are proton pump inhibitors (PPIs) used to treat gastroesophageal reflux disease (GERD) and erosive esophagitis.

What Are Possible Side Effects of Protonix?

Side effects of Protonix include:

  • injection site reactions (redness, pain, swelling),
  • headache,
  • nausea,
  • vomiting,
  • abdominal or stomach pain,
  • diarrhea,
  • gas,
  • dizziness,
  • joint pain,
  • weight changes,
  • drowsiness,
  • tired feeling, or
  • sleep problems (insomnia).

What Are Possible Side Effects of Dexilant?

Common side effects of Dexilant include:

  • diarrhea,
  • nausea,
  • vomiting,
  • stomach pain,
  • gas,
  • stuffy nose,
  • sneezing, or
  • other cold symptoms

What is Protonix?

What is Protonix?

Protonix IV (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis in adult patients.

What is Dexilant?

What is Dexilant?

Dexilant (dexlansoprazole) is a proton pump inhibitor (PPI) used to treat certain stomach and esophagus problems (such as acid reflux). It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

What Drugs Interact With Protonix?

Protonix may interact with atazanavir, blood thinners, digoxin, diuretics (water pills), ketoconazole, or methotrexate.

Protonix may also interact with nelfinavir, ampicillin, or iron.

What Drugs Interact With Dexilant?

Dexilant may interact with atazanavir, ampicillin, digoxin, iron, blood thinners such as warfarin, or ketoconazole.

Dexilant may also interact with digoxin, tacrolimus, or clopidogrel.

How Should Protonix Be Taken?

The recommended adult dose of Protonix is 40 mg once daily.

  • Protonix Oral Suspension should be taken 30 minutes before a meal
  • Protonix Oral Suspension should only be taken with applesauce or apple juice 30 minutes before a meal.
  • Protonix Oral Suspension should not be taken in or with water or other liquids, or with other foods.
  • Protonix Oral Suspension should not be chewed or crushed.
  • Protonix Oral Suspension packet should not be divided to make a smaller dose.

How Should Dexilant Be Taken?

The recommended dosage of Dexilant SoluTab is 30 mg once daily for up to 6 months for maintenance of healed EE, and 30 mg once daily for 4 weeks to treat symptomatic non-erosive GERD.

Reviewed on 4/4/2018


SOURCE:
RxList. Protonix Medication Guide.
https://www.rxlist.com/protonix-drug.htm#medguide
RxList. Dexilant Medication Guide.
https://www.rxlist.com/dexilant-drug.htm#medguide

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