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Last reviewed on RxList: 9/1/2016
Pyridium Side Effects Center

Last reviewed on RxList 8/31/2016

Pyridium (phenazopyridine hydrochloride) is an analgesic pain reliever used to treat pain, burning, increased urination, and increased urge to urinate. These symptoms are usually caused by:

  • infection,
  • injury,
  • surgery,
  • catheter,
  • or other conditions that irritate the lower urinary tract.
Pyridium treats the symptoms of a urinary tract infection, but does not treat the actual infection. Pyridium is available in generic form. Common side effects of Pyridium include: Tell your doctor if you experience serious side effects of Pyridium including:

The adult dosage of Pyridium is two 200 mg tablets 3 times a day after meals. Other drugs may interact with Pyridium. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Pyridium should be used only if prescribed. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Our Pyridium (phenazopyridine hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pyridium Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using phenazopyridine and call your doctor at once if you have any of these serious side effects:

  • pale skin, fever, confusion or weakness;
  • jaundice (yellowing of your skin or eyes);
  • urinating less than usual or not at all;
  • drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;
  • swelling, weight gain, feeling short of breath; or
  • blue or purple coloring in your skin.

Less serious side effects may include:

  • headache;
  • dizziness;
  • stomach pain, upset stomach; or
  • skin itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Pyridium (Phenazopyridine)

Pyridium Professional Information


Headache, rash, pruritus and occasional gastrointestinal disturbance. An anaphylactoid-like reaction has been described. Methemoglobinemia, hemolytic anemia, renal and hepatic toxicity have been reported, usually at overdosage levels (see OVERDOSAGE section).

Read the entire FDA prescribing information for Pyridium (Phenazopyridine)

Related Resources for Pyridium

Read the Pyridium User Reviews »

© Pyridium Patient Information is supplied by Cerner Multum, Inc. and Pyridium Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.


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