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Quelicin, Anectine vs. Atracurium

Reviewed on 10/1/2019

Are Quelicin, Anectine and Atracurium the Same Thing?

Quelicin and Anectine (succinylcholine chloride) and atracurium besylate injection are skeletal muscle relaxants used as adjuncts to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Side effects of Quelicin and Anectine and atracurium besylate that are similar include fast or slow heart rate and low blood pressure.

Side effects of Quelicin and Anectine that are different from atracurium besylate include cardiac arrest, dangerously fast rise in body temperature, arrhythmias, high blood pressure, high levels of potassium in the blood, prolonged respiratory depression or apnea, increased eye pressure, muscle twitching, jaw rigidity, postoperative muscle pain, acute kidney failure, excessive salivation, and rash.

Side effects of atracurium besylate that are different from Quelicin and Anectine include skin flushing or redness, injection site reactions, hives, itching, wheezing, shortness of breath, allergic reactions, and inadequate musculoskeletal block.

Both Quelicin and Anectine and atracurium besylate may interact with antibiotics, quinidine, procainamide, lithium, isoflurane, and magnesium salts.

Quelicin and Anectine may also interact with promazine, oxytocin, aprotinin, p-adrenergic blockers, lidocaine, trimethaphan, quinine, chloroquine, diethylether, desflurane, metoclopramide, terbutaline, oral contraceptives, glucocorticoids, and monoamine oxidase inhibitors.

Atracurium besylate may also interact with enflurane, halothane, other muscle relaxants, and succinylcholine.

What Are Possible Side Effects of Quelicin, Anectine?

Common side effects of Quelicin, Anectine include:

What Are Possible Side Effects of Atracurium?

Common side effects of Atracurium include:

What Is Quelicin, Anectine?

Quelicin, Anectine (succinylcholine chloride) Injection is a short-acting depolarizing skeletal muscle relaxant used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

What Is Atracurium?

Atracurium (loteprednol etabonate and tobramycin) is a combination of a corticosteroid and an antibiotic used to treat eye inflammation caused by surgery, infection, allergies, and other conditions. Common side effects of Atracurium include stinging, burning, irritation, itching, discomfort, or redness of the eyes for 1 to 2 minutes when this medication is applied.

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What Drugs Interact With Quelicin, Anectine?

Quelicin may interact with promazine oxytocin aprotinin antibiotics quinidine p-adrenergic blockers procainamide lidocaine trimethaphan lithium carbonate magnesium salts quinine chloroquine diethylether isoflurane desflurane metoclopramide terbutaline oral contraceptives glucocorticoids or monoamine oxidase inhibitors. Tell your doctor all medications and supplements you use. During pregnancy Quelicin should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Atracurium?

Atracurium besylate injection may interact with enflurane, isoflurane, halothane, antibiotics, lithium, magnesium salts, procainamide, quinidine, other muscle relaxants, and succinylcholine. Tell your doctor all medications and supplements you use. During pregnancy, atracurium besylate should be used only if prescribed It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Quelicin, Anectine Be Taken?

The dosage of Quelicin is individualized and should always be determined by the physician after careful assessment of the patient.

How Should Atracurium Be Taken?

An atracurium besylate dose of 0.4 to 0.5 mg/kg (1.7 to 2.2 times the ED95), given as an intravenous bolus injection, is the recommended initial dose for most patients.

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References


Pfizer. Quelicin Product Information.

https://www.pfizer.com/products/product-detail/quelicin_trade

Sagent Pharma. Atracurium Product Information.

https://www.sagentpharma.com/wp-content/uploads/2015/04/Atracurium-Besylate_PI.pdf

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