Reblozyl vs. Procrit

Reviewed on 12/10/2019

Are Reblozyl and Procrit the Same Thing?

Reblozyl (luspatercept-aamt) and Procrit (epoetin alfa) are used to treat different types of anemia.

Reblozyl is used to treat anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions.

Procrit is used to treat anemia associated with kidney failure, HIV patients undergoing treatment, cancer patients undergoing therapy, and certain surgical patients.

Reblozyl is an erythroid maturation agent and Procrit is a glycoprotein.

Side effects of Reblozyl and Procrit that are similar include headache, bone pain, joint pain, fatigue, cough, diarrhea, dizziness, nausea, and high blood pressure (hypertension).

Side effects of Reblozyl that are different from Procrit include abdominal pain, influenza, high uric acid levels in the blood, and viral upper respiratory tract infection.

Side effects of Procrit that are different from Reblozyl include muscle pain or spasms, body aches, vomiting, trouble swallowing, swelling, depression, weight loss, sleep problems (insomnia), pain/tenderness/irritation where Procrit is injected, and cold symptoms (stuffy nose, sneezing, sore throat).

Both Reblozyl and Procrit may interact with other medicines.

What Are Possible Side Effects of Reblozyl?

Side effects of Reblozyl include:

  • headache,
  • bone pain,
  • joint pain,
  • fatigue,
  • cough,
  • abdominal pain,
  • diarrhea,
  • dizziness,
  • nausea,
  • influenza,
  • high blood pressure (hypertension),
  • high uric acid levels in the blood,
  • viral upper respiratory tract infection, and
  • cough

What Are Possible Side Effects of Procrit?

Common side effects of Procrit include:

  • high blood pressure (hypertension),
  • headache,
  • joint pain,
  • bone pain,
  • muscle pain or spasms,
  • body aches,
  • nausea,
  • vomiting,
  • trouble swallowing,
  • swelling,
  • fatigue,
  • dizziness,
  • depression,
  • diarrhea,
  • weight loss,
  • sleep problems (insomnia),
  • pain/tenderness/irritation where Procrit is injected, or
  • cold symptoms (stuffy nose, sneezing, cough, sore throat).

Serious side effects of Procrit include:

What Is Reblozyl?

Reblozyl (luspatercept-aamt) is an erythroid maturation agent indicated for the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions.

What Is Procrit?

Procrit (epoetin alfa) is a glycoprotein that stimulates red blood cell production used to treat anemia associated with kidney failure, HIV patients undergoing treatment, cancer patients undergoing therapy, and certain surgical patients.

SLIDESHOW

Understanding Cancer: Metastasis, Stages of Cancer, and More See Slideshow

What Drugs Interact With Reblozyl?

Reblozyl may interact with other medicines.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Procrit?

Procrit may interact with other drugs.

Tell your doctor all medications and supplements you use.

How Should Reblozyl Be Taken?

The recommended starting dose of Reblozyl is 1 mg/kg once every 3 weeks by subcutaneous injection.

How Should Procrit Be Taken?

Procrit is available in vials; 1 mL of solution contains 2000, 3000, 4000 or 10,000 Units of Epoetin alfa. Single and multidose vials are available. Dose is determined by the prescribing doctor and the patient's condition.

QUESTION

Sickle cell disease is named after a farming tool. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Celgene. Reblozyl Product Information.

https://www.reblozylpro.com/

Janssen Products. Procrit Product Information.

https://www.procrit.com

Health Solutions From Our Sponsors