Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Requip vs. Horizant

Are Requip and Horizant the Same Thing?

Requip (ropinirole) and Horizant (gabapentin enacarbil) are used to treat restless legs syndrome (RLS).

Requip is also used to treat symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Requip and Horizant belong to different drug classes. Requip is a non-ergoline dopamine agonist and

Horizant is an anticonvulsant.

Side effects of Requip and Horizant that are similar include drowsiness, dizziness, and blurred vision or vision problems.

Side effects of Requip that are different from Horizant include nausea, vomiting, stomach pain, loss of appetite, worsened RLS symptoms early in the morning, diarrhea, constipation, dry mouth, sweating, headache, sleep problems (insomnia), agitation, anxiety, flushing, weakness, chest pain, leg swelling, high or low blood pressure, lightheadedness or fainting, muscle spasm, numbness, spinning sensation, abdominal pain, indigestion, gas, palpitations, fast heart rate, sore throat, or urinary tract infection (UTI).

Side effects of Horizant that are different from Requip include sleepiness and loss of coordination. Rarely, depression, suicidal thoughts or attempts, or other mental/mood problems may occur while taking Horizant. Tell your doctor immediately if this occurs.

Both Requip and Horizant may interact with alcohol and other drugs that make you sleepy (sleeping pills, narcotics, muscle relaxers, or medicines for anxiety, depression, or seizures).

Requip may also interact with levodopa, ciprofloxacin, fluvoxamine, metoclopramide, omeprazole, medications used to treat nausea and vomiting, medications used to treat mental illness, or estrogen.

Horizant may also interact with other medications that contain gabapentin.

Withdrawal symptoms may occur if you suddenly stop taking Requip.

What Are Possible Side Effects of Requip?

Common side effects of Requip include:

  • nausea,
  • vomiting,
  • stomach pain,
  • loss of appetite,
  • worsened RLS symptoms early in the morning,
  • diarrhea,
  • constipation,
  • dry mouth,
  • sweating,
  • headache,
  • dizziness,
  • drowsiness,
  • sleep problems (insomnia),
  • agitation,
  • anxiety,
  • flushing,
  • weakness,
  • chest pain,
  • leg swelling,
  • high or low blood pressure,
  • lightheadedness or fainting,
  • muscle spasm,
  • numbness,
  • spinning sensation,
  • abdominal pain,
  • indigestion,
  • gas,
  • palpitations,
  • fast heart rate,
  • sore throat,
  • urinary tract infection, or
  • vision problems.

What Are Possible Side Effects of Horizant?

Common side effects of Horizant include:

  • sleepiness,
  • drowsiness,
  • dizziness,
  • loss of coordination, or
  • blurred vision.

A small number of people who take anticonvulsants such as Horizant may experience depression, suicidal thoughts or attempts, or other mental/mood problems. Tell your doctor immediately if this occurs.

SLIDESHOW

Sleep Disorders: Insomnia, Sleep Apnea, and More See Slideshow

What Is Requip?

Requip (ropinirole) is a non-ergoline dopamine agonist used to treat symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Requip is also used to treat restless legs syndrome (RLS). Requip is available in generic form.

What Is Horizant?

Horizant (gabapentin enacarbil) is an anticonvulsant drug prescribed for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS) in adults. Horizant is not recommended for patients who are required to sleep during the daytime and remain awake at night.

What Drugs Interact With Requip?

Requip may interact with levodopa, ciprofloxacin, fluvoxamine, metoclopramide, omeprazole, medication used to treat nausea and vomiting or mental illness, or estrogen. Tell your doctor all medications you use. During pregnancy, Requip should be used only if prescribed. It is not known whether this medication passes into breast milk or if it could harm a nursing baby. Requip may reduce breast milk production. Consult your doctor before breast-feeding. Withdrawal symptoms such as fever, muscle stiffness, and confusion may occur if you stop the medication suddenly or if you change doses.

What Drugs Interact With Horizant?

Horizant may interact with other medications that contain gabapentin, and other products that cause drowsiness including alcohol, antihistamines, drugs for sleep or anxiety, muscle relaxants, narcotic pain relievers, and allergy or cough-and-cold products. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Horizant; it is unknown if it would affect a fetus. You should tell your doctor if you are breastfeeding or plan to breastfeed. In the body, Horizant becomes a drug called gabapentin that passes into your milk.

QUESTION

What kind of disorder is restless leg syndrome (RLS)? See Answer

How Should Requip Be Taken?

The recommended dose of Requip is 40 to 320 mcg twice daily for adults and 40 to 80 mcg twice daily for children. If you are also using a bronchodilator, use it first before using the beclomethasone inhaler. There may be other drugs that can interact with Requip.

How Should Horizant Be Taken?

Horizant is to be taken once per day with food at about 5 PM. Tablets should be swallowed whole and should not be cut, crushed, or chewed.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

Reviewed on 4/8/2019
References
SOURCE:

GSK. Requip Product Information.

https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Requip/pdf/REQUIP-PI-PIL.PDF

Arbor Pharmaceuticals. Horizant Product Information.

https://www.horizant.com/
CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors