Definition of Retinoic acid syndrome

Reviewed on 3/29/2021

Retinoic acid syndrome: A disorder due to the cancer treatment retinoic acid characterized by fever, difficulty breathing, chest pain, lung infiltrates, fluid around the lungs and heart, and hypoxia (lack of oxygen) that develops in some patients receiving retinoic acid therapy. It usually develops within 30 days of treatment. Steroids and chemotherapy can be used to treat retinoic acid syndrome.

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