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Last reviewed on RxList: 4/25/2017
Rimso-50 Side Effects Center

Last reviewed on RxList 1/31/2016

Rimso-50 (dimethyl sulfoxide, also called DMSO) is and anti-inflammatory and bladder irrigating drug believed to reduce swelling and pain due to interstitial cystitis and improve blood supply to the treated area used to treat pain and swelling associated with bladder or urinary conditions including cystitis (bladder inflammation or irritation). Common side effects of Rimso-50 include bladder pain and discomfort. A garlic-like taste in the mouth may be noticed within minutes of placing Rimso-50 in the bladder. This taste may last several hours, and an odor on the breath or from the skin may be noticed for up to 3 days following use of Rimso-50.

A 50 mL dose of Rimso-50 is administered directly into the bladder by catheter or syringe and allowed to remain for 15 minutes. This is done in a clinical setting. Other drugs may interact with Rimso-50. Tell your doctor all prescription and over-the-counter medications and supplements you use. Rimso-50 should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Rimso-50 (dimethyl sulfoxide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Rimso-50 Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers if you feel severe discomfort or irritation when the medication is inserted or while you are holding it in your bladder. This discomfort may become less noticeable over time with repeat treatments.

You may notice a garlic- or onion-like taste in your mouth while you are receiving dimethyl sulfoxide. This effect may last for several hours after you receive the medication, and you may also sense these odors on your breath or skin. This is a normal side effect of dimethyl sulfoxide and is not cause for concern.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Rimso-50 (DMSO)

Rimso-50 Professional Information


A garlic-like taste may be noted by the patient within a few minutes after instillation of RIMSO-50® brand of dimethyl sulfoxide. This taste may last several hours and because of the presence of metabolites, an odor on the breath and skin may remain for 72 hours.

Transient chemical cystitis has been noted following instillation of dimethyl sulfoxide.

The patient may experience moderately severe discomfort on administration. Usually this becomes less prominent with repeated administration.

Drug Abuse and Dependence: None known.

Read the entire FDA prescribing information for Rimso-50 (DMSO)

Related Resources for Rimso-50

Read the Rimso-50 User Reviews »

© Rimso-50 Patient Information is supplied by Cerner Multum, Inc. and Rimso-50 Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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