Rituxan vs. Tysabri

Are Rituxan and Tysabri the Same Thing?

Rituxan (rituximab) and Tysabri (natalizumab) are monoclonal antibodies used to treat multiple sclerosis (MS).

Rituxan is used off-label to treat MS.

Rituxan is also used in combination with other cancer medicines to treat non-Hodgkin's lymphoma, and in combination with another drug called methotrexate to treat symptoms of adult rheumatoid arthritis.

Tysabri is also used to treat moderate to severe Crohn's disease in adults. Tysabri is usually given after other Crohn's disease medications have been tried without successful treatment of this condition.

What Are Possible Side Effects of Rituxan?

Common side effects of Rituxan include:

Tell your doctor if you experience serious side effects of Rituxan including:

  • increased thirst or urination,
  • swelling of the hands or feet, or
  • tingling of the hands or feet.

What Are Possible Side Effects of Tysabri?

Common side effects of Tysabri include:

Tell your doctor if you have side effects while Tysabri is being given or shortly after your treatment is finished (infusion reaction) including:

  • chills,
  • fever,
  • flushing,
  • nausea,
  • dizziness, and
  • chest pain.

What is Rituxan?

Rituxan (rituximab) is a cancer medication used in combination with other cancer medicines to treat non-Hodgkin's lymphoma. Rituxan is also used in combination with another drug called methotrexate to treat symptoms of adult rheumatoid arthritis.

What is Tysabri?

Tysabri (natalizumab) is a monoclonal antibody used in to treat relapsing forms of multiple sclerosis. Tysabri is also used to treat moderate to severe Crohn's disease in adults. Tysabri is usually given after other Crohn's disease medications have been tried without successful treatment of this condition.

SLIDESHOW

What Is Multiple Sclerosis? MS Symptoms, Causes, Diagnosis See Slideshow

What Drugs Interact With Rituxan?

Rituxan may interact with cisplatin, adalimumab, auranofin, azathioprine, cyclosporine, etanercept, infliximab, leflunomide, minocycline, sulfasalazine, blood pressure medications, or medication to treat malaria.

What Drugs Interact With Tysabri?

Tysabri may interact with other medicines, especially those that may affect the immune system such as: interferon, cyclosporine, sirolimus, tacrolimus, basiliximab, efalizumab, muromonab-CD3, mycophenolate mofetil, azathioprine, leflunomide, etanercept, or chemotherapy or radiation treatments.

How Should Rituxan Be Taken?

Rituxan is administered under a physician's supervision. The dose of Rituxan varies depending on the disorder being treated and the number of infusions (doses) needed.

How Should Tysabri Be Taken?

The recommended dose of Tysabri for multiple sclerosis or Crohn's disease is 300 mg intravenous infusion over one hour every four weeks.

QUESTION

What kind of disease is multiple sclerosis? See Answer
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References


Genentech. Rituxan Product Monograph.

http://www.rituxan.com/

Biogen. Tysabri Product Monograph.

https://www.tysabri.com

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