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Robinul vs. Cuvposa

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Are Robinul and Cuvposa the Same Thing?

Robinul Injection (glycopyrrolate) and Cuvposa (glycopyrrolate) are anticholinergics that help to control conditions such as peptic ulcers that involve excessive stomach acid production.

The injectable form of Robinul is also used to reduce saliva, nasal, lung, and stomach.

Cuvposa is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

Side effects of Robinul and Cuvposa that are similar include drowsiness, dizziness, blurred vision, dry mouth, vomiting, constipation, stuffy nose, sinus pain, or flushing (warmth, redness, or tingly feeling).

Side effects of Robinul that are different from Cuvposa include weakness, dry eyes, or abdominal bloating.

Both Robinul and Cuvposa may interact with alcohol or amantadine.

Robinul may also interact with quinidine, antihistamines, decongestants, appetite suppressants, phenothiazines, or antidepressants.

Cuvposa may also interact with atenolol, digoxin, haloperidol, levodopa, or metformin.

What Are Possible Side Effects of Robinul?

Common side effects of Robinul include:

  • drowsiness,
  • dizziness,
  • weakness,
  • blurred vision,
  • dry eyes,
  • dry mouth,
  • vomiting,
  • constipation,
  • abdominal bloating,
  • stuffy nose,
  • sinus pain, or
  • flushing (warmth, redness, or tingly feeling).

Tell your doctor if you experience unlikely but serious side effects of Robinul Injection including:

  • decreased sweating,
  • fast/irregular heartbeat,
  • mental/mood changes (such as confusion, hallucinations, agitation, nervousness, unusual excitement),
  • difficulty urinating, or
  • decreased sexual ability.

What Are Possible Side Effects of Cuvposa?

Common side effects of Cuvposa include:

  • drowsiness,
  • dizziness,
  • blurred vision,
  • dry mouth,
  • stuffy nose,
  • sinus pain,
  • constipation,
  • vomiting, or
  • flushing (warmth, redness, or tingly feeling).

Tell your doctor if you have serious side effects of Cuvposa including:

  • stomach or abdominal bloating or pain,
  • persistent constipation,
  • persistent nausea or vomiting,
  • diarrhea,
  • decreased sweating,
  • fast or irregular heartbeat,
  • mental/mood changes (such as confusion, hallucinations, agitation, nervousness, unusual excitement), or
  • difficulty urinating or inability to urinate.

What Is Robinul?

Robinul Injection (glycopyrrolate) is an anticholinergic that helps to control conditions such as peptic ulcers that involve excessive stomach acid production. The injectable form of Robinul is also used to reduce saliva, nasal, lung, and stomach secretions and to help control heart rate during surgery. Robinul Injection is available in generic form.

What Is Cuvposa?

Cuvposa (glycopyrrolate) Oral Solution is an anticholinergic drug used to control conditions such as peptic ulcers that involve excessive stomach acid production. Cuvposa is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

What Drugs Interact With Robinul?

Robinul may interact with amantadine, quinidine, antihistamines, decongestants, appetite suppressants, phenothiazines, or antidepressants. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy, Robinul should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Cuvposa?

Cuvposa may interact with amantadine, atenolol, digoxin, haloperidol, levodopa, or metformin. Tell your doctor all medications and supplements you use. During pregnancy, Cuvposa should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Robinul Be Taken?

Robinul injection is administered intramuscularly (IM) or intravenously (IV), under a physician's supervision. Dose depends on the condition being treated.

How Should Cuvposa Be Taken?

The initial dose of Cuvposa is 0.02 mg/kg orally three times daily, and then adjusted in increments of 0.02 mg/kg every 5-7 days based on the patient's response and adverse reactions. The maximum recommended dosage is 0.1 mg/kg three times daily not to exceed 1.5-3 mg per dose based upon weight.

Reviewed on 4/15/2019

SOURCE:

Mylan. Glycopyrrolate (Robinul) Product Information.

https://www.mylan.com/en/products/product-catalog/product-profile-page?id=402197af-c04e-455a-9eed-c1249f187dc7

Merz Pharmaceuticals, LLC. Cuvposa Product Information.

https://www.cuvposa.com/

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