Rocklatan

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 8/6/2021
Rocklatan Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Rocklatan?

Rocklatan (netarsudil and latanoprost ophthalmic solution) a fixed dose combination of a Rho kinase inhibitor and a prostaglandin F2a analogue indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

What Are Side Effects of Rocklatan?

Common side effects of Rocklatan include:

  • eye redness,
  • instillation site pain,
  • whorl-like pattern of golden brown or gray deposits in the eye (corneal verticillata), and
  • broken blood vessels in the eye

Dosage for Rocklatan

The dose of Rocklatan is one drop in the affected eye(s) once daily in the evening.

What Drugs, Substances, or Supplements Interact with Rocklatan?

Rocklatan may interact with thimerosal used at the same time prostaglandins or prostaglandin analogs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Rocklatan; it is unknown how it would affect a fetus. It is unknown if Rocklatan passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Rocklatan (netarsudil and latanoprost ophthalmic solution) 0.02%/0.005%, for Topical Ophthalmic Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

What causes dry eyes? See Answer
Rocklatan Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using latanoprost and call your doctor at once if you have:

  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);
  • red, swollen, or itchy eyelids;
  • vision changes; or
  • severe burning, stinging, or irritation after using this medicine.

Common side effects may include:

  • eye pain after using the drops;
  • eye redness; or
  • changes to the surface of your eye that can be seen on an eye exam but are not likely to affect your vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Rocklatan (Netarsudil and Latanoprost Ophthalmic Solution)

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow
Rocklatan Professional Information

SIDE EFFECTS

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

The most common ocular adverse reaction observed in controlled clinical studies with ROCKLATAN was conjunctival hyperemia which was reported in 59% of patients. Five percent of patients discontinued therapy due to conjunctival hyperemia. Other common ocular adverse reactions reported were: instillation site pain (20%), corneal verticillata (15%), and conjunctival hemorrhage (11%). Eye pruritus, visual acuity reduced, increased lacrimation, instillation site discomfort, and blurred vision were reported in 5- 8% of patients.

Other adverse reactions that have been reported with the individual components and not listed above include:

  • Netarsudil 0.02%

Instillation site erythema, corneal staining, increased lacrimation, and erythema of eyelid.

  • Latanoprost 0.005%

Foreign body sensation, punctate keratitis, burning and stinging, itching, increased pigmentation of the iris, excessive tearing, eyelid discomfort, dry eye, eye pain, eyelid margin crusting, erythema of the eyelid, upper respiratory tract infection/nasopharyngitis/influenza, photophobia, eyelid edema, myalgia/arthralgia/back pain, and rash/allergic reactions.

Read the entire FDA prescribing information for Rocklatan (Netarsudil and Latanoprost Ophthalmic Solution)

© Rocklatan Patient Information is supplied by Cerner Multum, Inc. and Rocklatan Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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