Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Definition of Rothmund-Thomson syndrome

Rothmund-Thomson syndrome: A hereditary disease that is characterized by progressive effects on multiple areas of the body, including the skin, hair, eyelashes, teeth, musculoskeletal system, blood, and eyes. Patients have an increased risk for developing cancer, especially osteosarcoma and skin cancer. Abbreviated RTS. RTS is inherited as an autosomal recessive trait and is caused by mutations in the RECQL4 gene on chromosome 8. This gene encodes a DNA helicase, an enzyme that promotes DNA unwinding, which permits many basic cellular processes to take place. Also known as poikiloderma congenita and poikiloderma atrophicans with cataract.


What percentage of the human body is water? See Answer

Health Solutions From Our Sponsors