Ruby-fill Side Effects Center

Last updated on RxList: 5/9/2019
Ruby-fill Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 5/9/2019

Ruby-Fill (rubidium Rb 82 generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous use. Rubidium Rb 82 chloride injection is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease. Common side effects of Ruby-Fill may include unintended radiation exposure.

The recommended weight-based dose of rubidium Rb 82 is between 10-30 Megabecquerels (MBq)/kg [0.27-0.81 millicuries (mCi)/kg]. Administer the single dose at a rate of 15 - 30 mL/minute through a catheter inserted into a large peripheral vein; do not exceed an infusion volume of 60 mL. Ruby-Fill may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant before receiving Ruby-Fill. Radiopharmaceuticals such as Ruby-Fill have the potential to cause fetal harm depending on the fetal stage of development and the magnitude of the radiation dose. Wait at least one hour after Ruby-Fill infusion to resume breastfeeding.

Our Ruby-Fill (rubidium Rb 82 generator) to produce rubidium Rb 82 chloride injection, for intravenous use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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SIDE EFFECTS

The following serious adverse reaction associated with the use of rubidium Rb 82 chloride was identified in clinical trials or post marketing reports. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Radiation Exposure

High level radiation exposure to the bone marrow has occurred in some patients due to Sr 82 and Sr 85 breakthrough in the eluate when an incorrect solution was used to elute the rubidium Rb 82 generator [see BOXED WARNING, WARNINGS AND PRECAUTIONS]. Excess radiation exposure has occurred in some patients who received rubidium Rb 82 chloride injection at clinical sites where generator eluate testing appeared insufficient [see BOXED WARNING, WARNINGS AND PRECAUTIONS, DOSAGE AND ADMINISTRATION].

Read the entire FDA prescribing information for Ruby-fill (Rubidium Rb 82 Generator)

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© Ruby-fill Patient Information is supplied by Cerner Multum, Inc. and Ruby-fill Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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