Scandonest Side Effects Center

Last updated on RxList: 6/2/2022
Scandonest Side Effects Center

What Is Scandonest?

Scandonest Plain (mepivacaine hydrochloride injection) and Scandonest L (mepivacaine hydrochloride and levonordefrin injection) are indicated for production of local anesthesia for dental procedures by infiltration or nerve block in adults and pediatric patients.

What Are Side Effects of Scandonest?

Common side effects of Scandonest Plain or Scandonest L include:

  • numbness and tingling of the lips, tongue, and oral tissues;
  • nervousness,
  • dizziness,
  • blurred vision,
  • tremors,
  • drowsiness,
  • convulsions,
  • unconsciousness, and
  • possible respiratory arrest,
  • sweating, and
  • lightheadedness.

Dosage for Scandonest

For infiltration and block injections in the upper or lower jaw, the average dose of 1 cartridge of Scandonest Plain or Scandonest L will usually suffice.

What Drugs, Substances, or Supplements Interact with Scandonest?

Scandonest Plain or Scandonest L may interact with other drugs. Tell your doctor all medications and supplements you use.

Scandonest During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Scandonest Plain or Scandonest L; it is unknown how it would affect a fetus. It is unknown if Scandonest Plain or Scandonest L pass into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Scandonest Plain (mepivacaine hydrochloride injection) and Scandonest L (mepivacaine hydrochloride and levonordefrin injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Scandonest Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives, itching, skin redness; nausea, vomiting, sweating, feeling hot; fast heartbeats; sneezing, difficult breathing; dizziness, fainting; swelling of your face, lips, tongue, or throat.

Tell your caregiver right away if you have:

  • numbness and tingling in your mouth or lips, metallic taste in your mouth;
  • ringing in your ears, blurred vision, slurred speech, headache;
  • confusion, depression, severe drowsiness, feeling like you might pass out;
  • slow heart rate, weak pulse, weak or shallow breathing;
  • fever, neck stiffness, increased sensitivity to light;
  • tremors or muscle twitching, feeling anxious or restless;
  • ongoing numbness, weakness, or loss of movement in your legs or feet;
  • loss of bladder or bowel control;
  • loss of feeling in your lower stomach, groin, or genitals;
  • painful or difficult urination; or
  • fast heart rate, rapid breathing, feeling hot.

Common side effects may include:

  • anxiety, feeling restless or excited;
  • depression, dizziness;
  • tremors; or
  • blurred vision, ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Scandonest (Mepivacaine Hydrochloride Injection)

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Scandonest Professional Information

SIDE EFFECTS

Reactions to SCANDONEST® are characteristic of those associated with other amide-type local anesthetics. Systemic adverse reactions involving the central nervous system and the cardiovascular system usually result from high plasma levels (which may be due to excessive dosage, rapid absorption, inadvertent intravascular injection, or slow metabolic degradation), injection technique, or volume of injection.

A small number of reactions may result from hypersensitivity, idiosyncrasy or diminished tolerance to normal dosage on the part of the patient.

Persistent paresthesias of the lips, tongue, and oral tissues have been reported with the use of mepivacaine, with slow, incomplete, or no recovery. These post-marketing events have been reported chiefly following nerve blocks in the mandible and have involved the trigeminal nerve and its branches.

Reactions involving the central nervous system are characterized by excitation and/or depression. Nervousness, dizziness, blurred vision, or tremors may occur followed by drowsiness, convulsions, unconsciousness, and possible respiratory arrest. Since excitement may be transient or absent, the first manifestations may be drowsiness merging into unconsciousness and respiratory arrest.

Cardiovascular reactions are depressant. They may be the result of direct drug effect or more commonly in dental practice, the result of vasovagal reaction, particularly if the patient is in the sitting position. Failure to recognize premonitory signs such as sweating, feeling of faintness, changes in pulse or sensorium may result in progressive cerebral hypoxia and seizure or serious cardiovascular catastrophe. Management consists of placing the patient in the recumbent position and administration of oxygen. Vasoactive drugs such as Ephedrine or Methoxamine may be administered intravenously.

Allergic reactions are rare and may occur as a result of sensitivity to the local anesthetic and are characterized by cutaneous lesions of delayed onset or urticaria, edema and other manifestations of allergy. The detection of sensitivity by skin testing is of limited value. As with other local anesthetics, anaphylactoid reactions to mepivacaine have occurred rarely. The reaction may be abrupt and severe and is not usually dose related. Localized puffiness and swelling may occur.

Read the entire FDA prescribing information for Scandonest (Mepivacaine Hydrochloride Injection)

© Scandonest Patient Information is supplied by Cerner Multum, Inc. and Scandonest Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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