Science is the world's general scientific publication with the largest circulation. For the sake of comparison, Science's only competitor, the prestigious English journal Nature, has one third the number of subscribers worldwide.
Science is published by the American Association for the Advancement of Science (the AAAS). An online was version is now also available (at sciencemag.org).
Science provides an unusual blend of two very different kinds of editorial material -- the most important news of the week in science and in science policy and a selection of scientific papers reporting the most significant breakthroughs in research (including many that are important to medicine). In this sense, Science is both a news magazine and a traditional scientific journal wrapped together under one cover.
In addition, Science often publishes special in-depth sections on a specific topic. Some are about scientific careers. Other are on research areas -- for example, the latest developments in biotechnology, parasitology, or the genome project.