Medical Definition of Peroxisome proliferator-activated receptor
Peroxisome proliferator-activated receptor: A member of the nuclear hormone receptor subfamily of transcription factors. Peroxisome proliferator-activated receptor is abbreviated as PPAR.
There are 3 known subtypes of PPARs -- PPAR-alpha, PPAR-delta, and PPAR-gamma. The gene for PPAR-gamma is in chromosome band 3p25. It regulates the development of adipocytes (fat cells).
PPAR-gamma also influences the prenatal survival of dizygotic (nonidentical) twins. Twins with the same type of PPAR-gamma may develop at the same pace. However, when the twins are carrying different versions of PPAR-gamma, one twin may develop at the expense of the other.Source: MedTerms™ Medical Dictionary
Last Editorial Review: 6/9/2016
Top RxList Drug News
- Eat More Fiber, Not Less, During Pelvic Radiotherapy?
- Regular Walking, Even if Minimal, Tied to Lower Death Risk
- FDA Approves CAR-T Cell Therapy to Treat Adults with Certain Types of Large B-Cell Lymphoma
- FDA Clears Ustekinumab (Stelara) for Plaque Psoriasis in Teens
- 'Alarming' Increase in Stroke Risk Factors