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Definition of Schistosome

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Schistosome: A parasitic trematode worm contracted from infested water that is capable of causing liver, gastrointestinal tract and bladder disease.

There are three main species of these trematode worms (flukes) -- Schistosoma haematobium, Schistosoma japonicum, and Schistosoma mansoni -- that produce disease in humans. The larval forms of the parasite live in freshwater snails. The cercaria (form of the parasite) is liberated from the snail burrow into skin, transforms to the schistosomulum stage, and migrates to the urinary tract (S. haematobium), liver or intestine (S. japonicum, S.mansoni) where the adult worms develop. Eggs are shed into the urinary tract or the intestine and hatch to form miracidia (yet another form of the parasite) which then infect snails, completing the life cycle of the parasite.

Adult schistosome worms can cause very serious tissue damage. Some schistosomes which cannot live within man nonetheless cause swimmer's itch.

Disease due to schistosomes is termed schistosomiasis or bilharzia after the shortlived German physician Theodor Bilharz (1825-1862).

Reviewed on 12/11/2018

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