Medical Definition of Factor X
Factor X: A coagulation factor, a substance in blood essential to the normal clotting process. Production of factor X takes place in the liver and requires vitamin K. The gene for factor X is located on chromosome 13 and is in band 13q34.
The "X" in factor X is the Roman numeral "ten." (All numbered coagulation factors bear Roman numerals.) Factor X became known because of a genetic condition in which the factor is lacking.
Factor X deficiency is inherited as an autosomal recessive trait manifest by prolonged nose bleeds, gastrointestinal hemorrhage, menorrhagia (abnormally heavy menstrual bleeding), hematuria (blood in the urine), and hemarthrosis (bleeding into joints). Pregnancy in women with factor X deficiency is often associated with adverse fetal outcomes (recurrent spontaneous abortion, placental abruption, and premature birth).
Factor X is also called Stuart-Prower factor named for 2 patients discovered to have this disorderSource: MedTerms™ Medical Dictionary
Last Editorial Review: 6/9/2016
Top RxList Drug News
- FDA Expands Approval of Sutent to Reduce the Risk of Kidney Cancer Returning
- FDA Approves New Treatment to Prevent Bleeding in Certain Patients with Hemophilia A
- FDA Approves Treatment for Rare Genetic Enzyme Disorder
- FDA Grants Marketing of the First Device Helping to Reduce the Symptoms of Opioid Withdrawal
- FDA Approves Pill with Sensor that Digitally Tracks if Patients Have Ingested their Medication