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Definition of Brugada syndrome

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Brugada syndrome: a genetic condition that results in abnormalities of the heart rhythm. These irregular heartbeats are present in the lower chambers of the heart (ventricles) and can lead to fainting, difficulty breathing, or sudden death. Brugada syndrome is inherited in an autosomal dominant pattern, meaning that one affected parent can pass the condition along to offspring. Other cases can occur due to new mutations in the genes and are not inherited from a parent. The genetic problem in Brugada syndrome can occur in several different genes. It is most common in people of Asian descent and is more common in men than in women. The signs and symptoms of Brugada syndrome, including sudden death, can occur from early infancy to late adulthood.

Reviewed on 9/7/2018

REFERENCE: Genetics Home Reference. Brugada Syndrome.

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