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Definition of Neurofibromatosis type 2

Neurofibromatosis type 2: A genetic disorder that is characterized by the growth of benign tumors of both acoustic nerves (the nerves to the ears). These tumors, called acoustic neuromas, cause tinnitus (ringing in the ears), hearing loss, and problems with balance. Abbreviated NF2. Other findings in NF2 include similar benign tumors of other nerves, meningiomas, and juvenile cataracts. NF2 is inherited in an autosomal dominant manner and is due to mutation in the NF2 gene on chromosome 22. About half of people with NF2 have a
new gene mutation. Prenatal testing is available. Also known as bilateral acoustic neurofibromatosis and central neurofibromatosis.

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Reviewed on 12/11/2018

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