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Definition of Paraneoplastic pemphigus (PNP)

Paraneoplastic pemphigus (PNP): a rare, often-fatal, autoimmune disease in which a person’s immune system attacks its own tissues causing painful blistering skin and mucous membranes. Paraneoplastic pemphigus is always associated with an underlying cancerous tumor. In a small number of cases, PNP may go away if the underlying cancer is cured.

Another term for paraneoplastic pemphigus is paraneoplastic autoimmune multiorgan syndrome (PAMS).


What is leukemia? See Answer
Reviewed on 12/27/2019
Grant J Anhalt, MD, et al. Paraneoplastic pemphigus. UpToDate. Updated: Oct 30, 2019.

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