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Definition of Tuberculin

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Tuberculin: A protein extracted from Mycobacterium tuberculosis that is used in a skin test to determine if a person has been exposed to tuberculosis. The tuberculin preparation in most common use today is purified protein derivative (PPD) tuberculin. PPD is injected (or multiple-punctured) into the skin. If a reaction is seen at and around the site of injection, the test is positive. The PPD tuberculin test done by intradermal injection is also known as the Mantoux test.

Reviewed on 12/11/2018

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