Medical Definition of Reuptake
Reuptake: The reabsorption of a secreted substance by the cell that originally produced and secreted it. The process of reuptake, for example, affects serotonin.
Serotonin is a neurotransmitter (a chemical messenger). It is produced by nerve cells in the brain and is used by nerves to communicate with one another. A nerve releases the serotonin that it has produced into the space surrounding it. The serotonin either travels across that space and attaches to receptors on the surface of nearby nerves or it attaches to receptors on the surface of the nerve that produced it, to be taken up by the nerve, recycled, and released again. This process is referred to as reuptake. A balance is reached for serotonin between attachment to the nearby nerves and reuptake. A medication that acts as a selective serotonin reuptake inhibitor (SSRI) blocks the reuptake of serotonin and thereby changes the level of serotonin in the brain.
Reuptake is sometimes written as re-uptake.Source: MedTerms™ Medical Dictionary
Last Editorial Review: 5/13/2016
Top RxList Drug News
- Eat More Fiber, Not Less, During Pelvic Radiotherapy?
- Regular Walking, Even if Minimal, Tied to Lower Death Risk
- FDA Approves CAR-T Cell Therapy to Treat Adults with Certain Types of Large B-Cell Lymphoma
- FDA Clears Ustekinumab (Stelara) for Plaque Psoriasis in Teens
- 'Alarming' Increase in Stroke Risk Factors