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Definition of Granuloma

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Granuloma: A granuloma is one of a number of forms of localized nodular inflammation found in tissues. The fact that a granuloma is localized is important. So is its nodularity. Granulomas have a typical pattern when examined under a microscope.

Granulomas can be caused by a variety of biologic, chemical and physical irritants of tissue.

A calcified granuloma is a granuloma containing calcium deposits. Since it usually takes some time for calcium to be deposited in a granuloma, it is generally assumed that a calcified granuloma is an old granuloma. For example, a calcified granuloma in the lung may be due to tuberculosis contracted years earlier that is now dormant.

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Reviewed on 12/12/2018

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