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Definition of Myelodysplastic syndrome

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Myelodysplastic syndrome: One of a group of disorders characterized by abnormal development of one or more of the cell lines that are normally found in the bone marrow. Patients can develop a variety of symptoms related to anemia, low or high white blood cell count, infections, and bleeding problems. Myelodysplastic syndrome may progress and become acute leukemia. The well-recognized myelodysplastic syndromes include refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, chronic myelomonocytic leukemia, chronic myelomonocytic leukemia in transformation, and unclassified myelodysplastic syndrome. Also known as preleukemia or smoldering leukemia.

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Reviewed on 12/12/2018

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