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Definition of Osteogenesis imperfecta

Osteogenesis imperfecta: A group of inherited connective tissue diseases, all of which result from mutations that affect collagen in connective tissue in the body, and all of which result in fragile bones. The best known types of osteogenesis imperfecta are types I and II. Also known as brittle bone disease.

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Reviewed on 12/12/2018
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