Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Definition of Pernicious anemia

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Pernicious anemia: Low red blood cell count caused by inadequate vitamin B12. Abbreviated PA. Patients with PA do not produce intrinsic factor (IF), a substance that allows the body to absorb vitamin B12 from foods. The resulting inadequacy of vitamin B12 hampers the production of red blood cells. PA can be treated by injection of vitamin B12: oral administration will not work because people with PA cannot absorb orally administered vitamin B12. Also known as Addison's anemia.

Reviewed on 12/27/2018

Health Solutions From Our Sponsors