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Definition of Vascular endothelial growth factor (VEGF)

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Vascular endothelial growth factor (VEGF): A substance made by cells that stimulates new blood vessel formation, a mitogen for vascular endothelial (vessel lining) cells.

VEGF is a polypeptide structurally related to platelet-derived growth factor (PDGF). The gene for VEGF is on chromosome 6p12.

Reviewed on 10/30/2018

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