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Definition of Cell cycle

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Cell cycle: The sequence of events within the cell between mitotic (cell) divisions. The cell cycle is conventionally divided into five phases: G0 (the gap); G1, (the first gap); S (the synthesis phase, during which the DNA is synthesized and replicated); G2 (the second gap); and M (mitosis). Cells that are not destined to divide again are considered to be in the G0 phase. The transition from G0 to G1 is thought to commit the cell to completing the cell cycle by dividing.

Reviewed on 12/27/2018

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