Nerve, hypoglossal: The hypoglossal nerve is the twelfth cranial nerve. The twelve cranial nerves, the hypoglossal nerve included, emerge from or enter the skull (the cranium), as opposed to the spinal nerves which emerge from the vertebral column.
Paralysis of the hypoglossal nerve affects the tongue. It impairs speech (it sounds thick) and causes the tongue to deviate toward the paralyzed side. In time, the tongue diminishes in size (atrophies).