I began with an IOP of 30 in each eye. I was prescribed Latanoprost once daily in each eye. After a month, Latanoprost had no effect. I was switched to Combigan. After 3 weeks using Combigan 2X daily, my IOP was down to 19 in each eye. I introduced 1 drop in each eye in the morning, and again in the evening about 12 hours later.
Related Reading: latanoprost | combigan
My Doctor started me on Combigan in April 2017. About a month after starting, I experienced severe dizziness I could not even stand. For months I walk around feeling light headed. After about nine months of taking Combigan, I noticed my eye getting very red and my eyelid beginning to droop. It totally changed my facial appearance. I had to stop taking this medication. Even though it effectively decreased my eye pressure, the side affects were to too much..I no longer take this medication.
Development of macular edema after 3 weeks of use!! Dr discontinued immediately but still have residual issues!
Related Reading: edema
From 
Eye Health Resources
Health Solutions From Our Sponsors
Medical Editor: John P. Cunha, DO, FACOEP
Combigan has lowered the intra ocular pressure in both eyes. However, I feel very tired and my blood pressure drops for 3-4 hours after each use.
Related Reading: combigan