Comment from: Shelli 35-44 Female 10 years or more Patient Published: April 12

My satisfaction level has to do with cost and insurance availability of this cream. I've been using this cream for 15 years. My insurance paid for it. When I take oral meds for cold sores I get migraines and they take 7-10 days to work. I can put this on if I even THINK I'm getting a sore and 1-2 doses is enough. I went 3-4yrs w/o a breakout and then had one. I thought the Pharmacy was joking when I heard $900 for a tube (it's over $1000 now). So I took the pills and took medication to help with the migraines and nausea. Seems stupid. But guess what I found when I started packing my house. A new large and small tube (they stopped making the 1.5g tube, but it cost $300 when I last got a quote). I felt like I'd won the lottery. And who gives a crap that it expired 6 and 8 years ago? I don't. It's sad that a company thinks they can charge that much! This the same crap that insulin users are having. I may not die from cold sores, but if I don't treat them I could lose my eye site when they walk up the nerve on my face.

Related Reading: cold sores

Comment from: Warmie 55-64 Female 5 to less than 10 years Patient Published: January 08

On board with all previous posts. The cost is absolutely ludicrous. I call it my GOLD medication. I fortunately had a wonderful Doctor who jumped through hoops and did all she could to get pre approval via medicare. I've used this medication for years and last year was the first time I had an issue with coverage. It still took 4 months to finally get approval. But, I got it and well worth the wait. I get sores whenever I'm stressed, sick or out in the sun to long. It's the only one I've used that actually works and takes the cracked, burning, scabbing and painful 4 wks of healing down to 1 wk without cracking and pain. This is a great medication. But, yep the cost is beyond comprehension. I feel for all of you and hope that you can get a doctor to help with the red tape to get it approved.

Comment from: Anwndwsn 45-54 Female less than 1 month Patient Published: December 03

I love it. If you apply at the first sign of a sore, it doesn't even pop up.

Comment from: klo47 55-64 Female Patient Published: May 23

My dr. prescribed Denavir. The pharmacy told me the cost is $1,000 and not covered by insurance! Who would pay that for a tube of cream. This is utterly ridiculous.

Related Reading: denavir

Comment from: 35-44 Female 10 years or more Patient Published: May 09

This works super well for me and my sons. I just went to get a refill and found out that it now costs $1530.88!!! WHAT???? are you kidding me. I have to choose if i want to make my house payment or get cold sore med? this is outa control.

Comment from: KK 55-64 Female less than 1 month Patient Published: February 12

Thank goodness the doctor gave me a sample as when I went to get it filled it was $500 with my insurance. Could not afford to get it filled.

Comment from: TcBW 35-44 Female less than 1 month Patient Published: January 08

This has been the only thing that has ever been able to keep a blister from forming if used at the first tingling signs. It can be pricey but is worth every penny if you suffer from bad outbreaks or frequent ones. A very tiny amount goes a long way so it will last a very long time.

Comment from: Queenbee 45-54 Female 5 to less than 10 years Patient Published: June 08

I have been using this product for years and it works great! I usually pay $50.00 for it but when I went to refill it today, I was told it is no longer covered and it cost $800.00. Who has $800.00 for a little tube? This is ridiculousness! No wonder health care is out control and people cant afford it.

Comment from: 55-64 Female 5 to less than 10 years Patient Published: April 13

I have been using denavir for years and years and it worked so good. Now my insurance wont cover it and out of pocket cost is $895.00. Seriously!! Who can afford that for a little tiny tube? Shame on these drug companies!! Makes me sick!

Related Reading: denavir

Comment from: tianya 65-74 Female 10 years or more Patient Published: March 12

I have been using this for my occasional cold sore. I am surprised that it costs $700 now as I paid $46 in 2010 at costco which was the cheapest at that time. I just got another flare up after almost 18 months and got it subsided in 3 days with this cream bought in 2010. To prevent waste, I use a snipped off dental pick as applicator to smear it over the affected area. You can remove just enough with the tip and not soaked up like a Q tip does. I also put the tube in another small plastic cylinder to keep it air tight. It won't be squashed easily in my purse or carry- on luggage when I travel.

Comment from: Jammerjoy 55-64 Female less than 1 month Patient Published: January 19

I met our insurance deductible so before the first of the year I had my prescription filled for denivar along with my usual medications, not paying attention to the cost because there was no charge, I later discovered that my Insurance company has to pay $700.00 !!!!!! No wonder insurance is expensive! I wouldn't blame my insurance company for dropping me. There should be a class action lawsuit against this pharmaceutical company. This has got to be illegal.there is no way a small tube of topical ointment for fever blisters should cost this much. Never again and be warned!!!

Comment from: Savannah 55-64 Female 10 years or more Patient Published: November 17

Like the others, used to get it for $15-30 copay, now $174.00, $700 w/o insurance. Who can even afford that? If a reasonable price can't be charged, package in much smaller tubes. This drug has been around for quite awhile, where are the generics when you need them?

Comment from: Queenee 45-54 Female Patient Published: October 08

Like everyone else...can't afford it/With my insurance it's still $5oo at Walmart, $700 at CVS...sorry but can they get away with this. 10 years ago my co pay covered it for $ this a MONOPOLY or what..

Comment from: mavido79 45-54 Female 10 years or more Patient Published: October 05

Was this drug bought by the same company that bought the AIDS drug and jacked up the price??? I've never paid more than a $25 co-pay for it in the past. Now my insurance doesn't cover it and it's $800. I gave it a single star on effectiveness because at these prices no one can afford to use it.

Related Reading: aids

Comment from: wen 45-54 Female less than 1 month Patient Published: August 27

I wanted to fill this cream again and it used to be 30.00 a tube but now it's 2, my Wal-Mart with my stinking insurance! Who has that much money for a tiny tube of cream.?

Comment from: 65-74 Female 5 to less than 10 years Patient Published: July 12

The treatment is effective. The current price is OUTRAGEOUS! In Feb. 2012 the cost was $112.39....Today, it's almost $700....What gives???

Related Reading: treatment

Comment from: 45-54 Female 2 to less than 5 years Patient Published: December 11


Comment from: Female Patient Published: June 09

Again, after using Denavir on my cold sore for four days, the cold sore turned into a red patch, like a hickey. It was much harder to cover up and it is lasting twice as long as it suppose too. Also, Denavir cost $603.01, for 5 g. at Walmart Pharm. Nothing should cost that much. When open, too much cream comes out the tube, that to me, is a waste of money.

Related Reading: denavir

Comment from: pmats 65-74 Female 5 to less than 10 years Patient Published: April 05

I have had fever blisters for many years for different reasons. Here's a tip......I use it on my lips before going to the dentist for a cleaning or a procedure. All that stretching of my lips can lead to an outbreak (and maybe the rubber glove material)but doing this before the appt avoids any problem. LOVE denavir!!!!!!

Related Reading: denavir

Comment from: Cpow 45-54 Female 5 to less than 10 years Patient Published: March 17

I have a whole routine when I get a cold sore. First, I ALWAYS have my Valtrex and Denavir on hand; as soon as I use them up I immediately get refills for the next outbreak, be it a few months or a year. They are with me when I travel. And have lots of qtips and tissue too. At the first sign, I start the Valtrex (the first 2 of 4 tablets). Then I start dabbing the spot with rubbing alcohol on a qtip. Let it dry then dab two or three more times. Each time using a clean qtip. Then apply Denavir. If I'm home I glob it on. Do this at least 3 times a day. Then take the last 2 tablets of Valtrex 8-10 hours or so later. Be VERY careful with contamination. After I brush my teeth I rinse my toothbrush in VERY hot water. When I'm sure the cold sore is completely gone I throw out the toothbrush and use a new one. After a shower or washing my face I don't dry my mouth area with my towel (I kind of inward pucker my lips to cover the cold sore). Then I take clean tissue and wipe my mouth area. Every time I do ANYTHING for the cold sore I immediately wash my hands. And try not to lick your lips either. My remedy does seem to dry out my lips a little but it's totally worth it 'cause it's drying out that dang cold sore quickly. Sometimes in as little as 3 days start to finish. Many years of trial and error and this really works well for me.

Related Reading: valtrex | denavir


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Medical Editor: John P. Cunha, DO, FACOEP

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