Comment from: 65-74 Female 6 months to less than 1 year Patient Published: November 18

When I fall asleep, it helps me stay asleep and have deeper sleep. I still have plenty of sleepless nights even though I take it regularly. I have to take it with food because it upsets my stomach.

Comment from: Ltb3105 55-64 Female less than 1 month Patient Published: October 28

This med is not fast acting. Take it at night only because once it kicks in, you will be out cold all night. Hated the groggy feeling in the morning, like a hangover. It was prescribed for nerve pain, not depression, and it didn't interact too well with Mobic I was taking for osteoarthritis. Within a few days, both ankles and feet swelled up and were more painful than my original pain I was taking the med for! Doctor had me go off it right away. Feeling a lot better without it.

Related Reading: depression | mobic | osteoarthritis

Comment from: Ltb3105 55-64 Female less than 1 month Patient Published: October 20

Trazodone was prescribed to help with nerve pain, making it difficult for me to sleep at night. Well, it knocks you out, but sneaks up on you, takes about an hour and a half. I slept soundly, but woke up and stayed groggy several hours. Less than a week after I started taking it, my ankles and feet swelled up. This hurt more than the original pain I was prescribed for! Went off it, and it took a few days for the swelling to go down. I'm more clear headed too. Stay clear of this one. And I'm one to not usually have any reactions. Oh, gave me carb cravings.

Related Reading: trazodone

Comment from: Emily T 65-74 Female less than 1 month Patient Published: November 25

This drug is POISON to your system. After only taking one dose, I have had 3 days of nausea, headache, extreme dizziness, and weakness in my legs. Never take this drug, it could kill you. I took a 50 mg dose and am a healthy 65 year old, waiting and praying for it to leave my system. The doctors that prescribe this poison ought to be forced to take it themselves

Related Reading: headache | dizziness

Comment from: rotty 45-54 Male 5 to less than 10 years Patient Published: December 17

This medication has done wonders for me. Not only does it help with my depression, it helps me get to sleep.I have been on 300mg for 8yrs and have had no problems.

Related Reading: depression

Comment from: 55-64 Male 1 to 6 months Patient Published: July 30

very good,wake up abit groggy at frist

Comment from: 55-64 Male 10 years or more Patient Published: February 16

Has been a consistent aid with little side effects.

Comment from: Tom 65-74 Male 10 years or more Patient Published: July 20

I've been taking this for 11 years after a bout of a week or more insomnia. I began with 50 ml and it worked great. It began loosing its affect after 4-5 years. So my Dr. Bumped me to 100 ml. It quit working as we'll several months ago so I decided to ween myself off of it. Big mistake! After many days of tryingHalcyon, Ambien, etc. I increased my dosage of Desryl to 150 and Eureka! I have had two good nights sleep in a row.

Related Reading: insomnia | ambien

Comment from: Paige 45-54 Female 10 years or more Patient Published: May 01

i have tried every drug out there for sleep and for insomnia (ambien, lunesta, benadryl) and the only thing that totally knocks me out is trazadone (desyrel). I have been taking it for many years and the effectiveness is still great now as it was 10 years ago. I wake up with no side effects like ambien or valium BUT it only lasts for 4-5 hours when I have to wake up and take the other half of a 300 mg pill but I don't care - what works works and I will never change what is not broken

Related Reading: insomnia | ambien | lunesta

Comment from: abbi100 65-74 Female Patient Published: April 17

Why is stuff like this prescribed for people with FMS..FIBROMYALGIA who already have muscle pain, this drug causes MUSCLE PAIN. You just doubled my pain level. I am not depressed, FMS makes your muscles so painful you can't find a spot that does not hurt to sleep on. You add in OA/OP and there is no spot that is not painful to sleep on. Selenium 100 mg at night seems to work far better, no side effects. Better than Melatonin.

Related Reading: fibromyalgia | muscle pain

Comment from: macrrt 45-54 Male 2 to less than 5 years Patient Published: February 21

I've had severe trouble falling and staying asleep do to GAD, and Severe Pain. I don't do well with 99.9% of anti-depressants. This drug however, has been a life saver for me I get a good nights sleep and am rested in the a.m. I take 400mgs at night and have had zero side effects for over 3 years.

Comment from: trazhater 25-34 Female less than 1 month Patient Published: October 21

Trazodone is the devil in disguise! This drug was LIFE CHANGING, and I do not mean for the better. I was prescribed 50 mg at night because I had insomnia. (no depression, just insomnia). I took the first pill that night, and the next day I was dizzy. All day. (dizzy is actually an understatement- there were times I could not drive it was that bad). I started to have anxiety. And it only got worse and worse. SEVERE anxiety, 24/7, dry mouth which caused no appetite, I lost 13 pounds in 3 weeks, constant crazy thoughts, I WAS NOT THE SAME PERSON! (I took it for 8 days total) It has been FIVE WEEKS since I stopped and the dizziness is JUST NOW starting to subside a little, and it's going very slowly. The anxiety started to improve last week, so that would be 4 weeks of severe anxiety this drug caused me. The drug is out of your bloodstream by 48 hours, however, I am living proof that it stays in your brain for quite some time. I do not know how people take this drug and function normally. It has forever changed me, I will always be cautious from now on what prescriptions I put into my body. I DO NOT recommend this drug to anyone!!

Related Reading: trazodone | insomnia | depression

Comment from: 45-54 Female less than 1 month Patient Published: October 11

I have not started yet because I want to read about it first.

Comment from: joyce 55-64 Female less than 1 month Patient Published: October 02

I was prescribed this drug as a sleep aid following detox from alchohol use. After one week of use, I began having dizzy spells, low blood pressure, nausea, and general disorientation. I've stopped using this drug and use an herbal tea instead. :)

Related Reading: low blood pressure

Comment from: Trazodon 55-64 Male 1 to 6 months Patient Published: July 17

I have only taken 1/2 of the pill, and it help me sleep for awhile, I just wanted to know more about this Medication.

Comment from: 35-44 Female 5 to less than 10 years Patient Published: May 27

This is the only med that has been effective for me to get a full night's rest for six years straight! I started at 100mg and am down to 50 mg. I attribute this success to the anxiety relief it provides, as well as the fairly fast effects. Please note, for max effectiveness, an established routine works best as far as what time to go to sleep, and you have to have a light snack with this-but other than that, easy to use. Just don't skip doses and always carry with you if you might not be at home-I can't sleep well without it. I'm sure this varies amongst others that might be on other meds that cause drowsiness.

Related Reading: anxiety

Comment from: Jamie 45-54 Female less than 1 month Patient Published: February 25

Menopause has brought on sleeplessness, alittle anxiety and hot flashes. My 50mg pill has helped all of these. I haven't been taking it long, though. I hope the benefits last. With a good night sleep, I have a lot more energy and happiness throughout the day - yippee!! The reviews are incredibly mixed - Trazedone results seem to be very individual. I also love that it's only $4 a month at Walmart since I don't have prescription coverage!

Related Reading: anxiety | hot flashes


Depression is a(n) __________ . See Answer
Comment from: regmayorga 45-54 Female 1 to 6 months Patient Published: February 10

The only thing I don't like is that if I take my pills to sleep they work very well however, If Im woken up no matter how long i slept whether it was 20 minutes ot a few hours, once I get up I cannot go back to sleep

Comment from: 55-64 Female less than 1 month Patient Published: November 25

not effective yet

Comment from: 65-74 Female 10 years or more Patient Published: October 02

long term use has proven now ineffective . Now need to stop but with difficulty r/t anxiey and nevvousness when weaning .I started this med when with a major depression , now past . It is effecting my hypotension . any sugestions "

Related Reading: depression


Medical Editor: John P. Cunha, DO, FACOEP

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