Comment from: dee 55-64 Female 10 years or more Patient Published: February 11

Ever since I had gallbladder removed I have had IBSD severely. Lotronox has been a life saver. However, now since taking it for over 10 years I have developed hive and rashes when taking it. Hives are really bad. So I had to stop. Nothing else works as well as lotronex. I wish I could go back to it but the hives has gotten so bad. No other side effects for the 10+ years I was on it. Not sure if anyone else has had this experience, but thought I should let you know.

Related Reading: hives | lotronex

Comment from: SB1234 45-54 Female 1 to 6 months Patient Published: December 29

It took awhile to get the right dose but after a few months I seem to be great on one half of a .05 mg tablet every other day. I try and make good food choices and drink plenty of water. I write down when I take the medicine and when I have a BM. This way I can back off if I need to to make sure I'm not getting C. (haven't had to do that since the first few weeks). Keep track of how much you take when you take it and your BM's. You think you'll remember but you won't. You can also just note it in your phone. So far so good I'm really on a schedule now. I actually ran errands after eating the other day I would NEVER have been able to eat and then go somewhere. I still wouldn't eat before my kids ballgames or going out but I need to try that soon as I haven't had D in months after I started this medicine, but when you've dealt with IBS for years its hard to relax and not worry in certain situations! It is now available in generic so I pay $15 a month with insurance. Don't know what I would do if they don't cover it. Can't imagine life without this now. If you are worried then read the medical reviews (studies/trials) since it was rereleased there have been no deaths or horrible incidents. Go slow and don't get discouraged it takes some time to adjust and see how much you need. I actually upped my dose for a week at the start but then now I'm at just a half every other day for months and I am on a good schedule with normal BM's. No more racing home to get to the bathroom or stopping on the way because I can't make it.

Comment from: ss 65-74 Female 1 to 6 months Patient Published: October 10

I suffered with IBS D for years & finally was prescribed Lotronex. I was at the point where I couldn't leave my home. This has been a real life saver.

Related Reading: lotronex

Comment from: 65-74 Male 10 years or more Patient Published: May 21

I have been on this drug before it was recalled and after it was brought back on the market. I am a male and this is causing my insurance company to reject paying for the drug. Drug cost started at $600 a month to now $3,300 a month in 2016.

Comment from: 35-44 Female 10 years or more Patient Published: October 22

Lotronex has given me my life back. Before I could not leave my house, missed significant amounts of work, did not want to eat (lost a lot of weight), and became depressed. I took Imodium like it was candy. With my Dr. we tried many different medications and changes in diet, but nothing worked. Lotronex was the last option and it was the best decision I could have made. The benefits by far outweigh the risks of taking the medication. I have been taking it for years now and they just released a generic brand. It has worked so well for me that I could not be happier to be able to have my life back.

Related Reading: lotronex | imodium

Comment from: chris 45-54 Female 1 to less than 2 years Patient Published: July 11

I took Lotronex the 1st time it was out and it was my miracle drug. It was devastating when taken of the market. I couldn't be happier that it's back and I'm on it again....it's a quality of life drug

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Comment from: Elise 55-64 Female 1 to less than 2 years Patient Published: October 08

I've got my life back.

Comment from: gingersnap 55-64 Female 5 to less than 10 years Patient Published: August 17

After years of uncontrolled diarrhea, my doctor prescribed this for me. It works great but each year the cost increased. I went to the drug manufacturer's web site and found a discount program offered. I only pay a fraction of the price now!

Related Reading: diarrhea

Comment from: bgjaws1958 45-54 Female 2 to less than 5 years Patient Published: August 12

After 20 years of pain and diarrhea, Lotronex gave me relief from both. I was educated on the product for over a year and for the first time could go days and then weeks without an episode. There are risks but a woman who takes care of her health can recognize the problem and stop the drug before any problems become dangerous.

Related Reading: diarrhea | lotronex

Comment from: stephanie 45-54 Female less than 1 month Patient Published: July 04

$2500 a month!!! that's enough to give me diarrhea.....only the rich could afford this, or maybe people on welfare.

Related Reading: diarrhea

Comment from: Lnh 65-74 Female 2 to less than 5 years Patient Published: June 29

I have taken Lotronex for four years for Functional Diarrhea. I had cancer of small intestine with removal of illeosecal valve and much of my small intestine. I also had a complication of diarrhea from overseas travel. I lost 30 lbs. and was reluctant to leave my home due to uncontrolled diarrhea that Stumped GI doctors until I found a GI Dr. Who put me on Lotronex as a last resort. Currently, I take Lotronex 1mg. Daily with 80 mg. Nortriptyline and 3 lomotil tabs with meals. Until I went on Medicare, I took 2mg. Lotronex daily with limited additional medications ; however Lotronex 2 x daily is now too expensive. With Lotronex, My quality of life has significantly improved and I seldom have to use tincture of opium. I hope that the price of Lotronex goes down for those on medicare. Anyone with chronic diarrhea should have access to this drug.

Related Reading: lotronex | diarrhea | cancer

Comment from: 45-54 Female 1 to less than 2 years Patient Published: March 20

This is truly a miracle drug. It can cause some constipation and bloating but if you adjust your diet you can control that.

Related Reading: constipation

Comment from: 65-74 Female 10 years or more Patient Published: December 30

It has improved my IBS-D about 50%. Without it, I am housebound. But the cost!!! $2,500 a month! It was $175 when introduced. This is greed, pure and simple. And no generic for years to come.

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Comment from: It's a miracle! 55-64 Female 5 to less than 10 years Patient Published: November 06

This truly is a miracle drug! I guess that is why the cost is so astronomical! It has worked wonders for me and I no longer have to be afraid of an embarrassing attack immediately after I eat something. I hope I am forever able to continue taking this drug. I am on a very low dosage so I would rather accept the risks than suffer the consequences by not taking it.

Comment from: silver queen 55-64 Female 2 to less than 5 years Patient Published: October 24

I had constant diarrhea for years which made travel almost impossible. I talked to my doctor and he told me about Lotronex and explained all the side effects. I decided to try and had to sign a paper saying I understood all about the drug and side effects. He prescribed the lowest dose and I have been on it for about 4 years and it works like a miracle. I have gotten my life back and can leave the house without any worries. I always wait until my morning "constitution" before taking my Lotronex and I am good to go for the day.

Related Reading: diarrhea | lotronex

Comment from: 75 or over Female 5 to less than 10 years Patient Published: September 15

I tried this medicine several years ago, but then I could not get it any more, and I was back to the earlier problems. I hope to be able to use this product again.

Comment from: Happyagain 45-54 Female less than 1 month Patient Published: May 22

I had addressed every issue,diet,food sensitivities etc but still dealt with the stress of IBS since chemo 20 yrs ago. I felt and do believe this drug has corrected an imbalance in my gut related to my treatments. I am a nurse and research in detail about this subject and nutrition . From the first dose I have had amazing results. I used to take 8 Imodium and 4 lomotil to be able to travel with iffy relief . My insurance covers it but if not I would give up other things to live my life normally like I am now able to do with lotronex.

Related Reading: stress | imodium | lomotil


Digestive Disorders: Common Misconceptions See Slideshow
Comment from: themortgagequeen 65-74 Female 5 to less than 10 years Patient Published: February 25

This drug is a GodSend to me. I cannot leave the house without this medication. However, I am now on ObamaCare and I am already in the doughnut hole for 2013 and it is only Feb. 25. I can not afford to pay for this wonder-drug, so until I can buy my way out of the hole, I am stuck at home. Incidentally, for 1mg. twice a day, a months prescription is $2,152, which is obscene. My co-pay, when I have the money, use to be about $100. Now, I have to pay the entire amount, which I cannot afford. If anyone has an answer, please advise. I am frantic. themortgagequeen

Comment from: correctusage 25-34 Female 1 to 6 months Patient Published: January 21

My doctor had me try this instead of relying on Imodium daily. I took .5 - 1.5 mg per day. The medication did make a difference, offering firmer stools 3 out of 4 times. It does not reduce the number of bowel movements as well as Imodium does, and it does not settle my uppity stomach as well as Imodium. Last year my insurance covered the cost 100% - Today, it was going to cost me, out of pocket, $1,500 for one month at three .5mg pills per day. That is AFTER my insurance contributed $1,000 and AFTER the manufacturers $500 discount card. For me, the benefit is not worth emptying my bank account and selling my house to stay on the medication. It was not a miracle for me, and I am not one of those who can use one .5mg pill every couple days, unfortunately.

Related Reading: imodium


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