Comment from: TheShakes 19-24 Male less than 1 month Patient Published: October 06

This is a terrible drug. I was given a dose when I went to the hospital with a multiple day old headache. About 10 minutes after the dose, I felt like I was dying. Nothing was wrong, but it felt like the world was ending. I heard loud ringing that felt like it was shaking the building, I couldn't catch my breath, I got severe tunnel vision, and started to lose control of my muscles. At 15 minutes, I had no control at all. I was unable to speak, think, move, and was almost blind. At 20 minutes, the convulsions started. Every muscle in my body began contracting at once. I came close to breaking a hospital bed from thrashing that day. To this day, I still have fits of the same symptoms out of the blue. This drug ruined my life. I would reccomend that anyone stay clear of this drug, so you don't have to live my experience.

Related Reading: headache

Comment from: Amitriptyline Steve 65-74 Male Patient Published: January 26

If standard antacid medications don't help, I suggest you try Amitriptyline before long-term use of Reglan. Read my review under the condition "feel like throwing up"

Related Reading: reglan

Comment from: Amitriptyline Steve 65-74 Male Patient Published: January 26

If your symtoms are IBD, gerd and/or heartburn, I suggest you try Amitriptyline before long-term use of Reglan. Read my review under the condition "feel like throwing up".

Related Reading: heartburn | reglan

Comment from: Amitriptyline Steve 65-74 Male Patient Published: January 26

I have never taken this drug but please read on. Eight months ago, while taking Cymbalta, I got a feeling of nausea that would not go away. I eventually stopped the Cymbalta but the nausea continued. Eventually it was 24/7. Doctors blamed it on anxiety and stomach acid. My dentist and my gastroenterologist confirmed I had a stomach acid problem. So for the next several months I was prescribed high dosages of H2 blockers and proton pump inhibitors. I only got worse. I now had stomach cramps in addition to my chronic nausea. Searching the internet, I discovered I had functional dyspepsia (i.e., indigestion that doesn't respond to normal treatments). I learned that that the drug of last choice (due to possible serious side effects) was this drug, Reglan. But I also learned that the anti-depressant Amitriptyline was often helpful at low dosages. (google functional dyspepsia and amitriptyline). I started 10 mg and worked up to 30 mg over a week. The nausea feeling changed to a lump in my throat feeling and the stomach pains vanished. I had the dosage increased to 75 mg but that caused really bad constipation, so I backed down to 50 mg. At this time, I no longer take antacid medication but I am almost symptom free. I have no stomach pain, no constipation, no lump in the throat, and only an occasional light nausea feeling that doesn't last all day. So, my advice to anyone considering Reglan is to first try Amitriptyline. It is much safer. It can help even if you are not suffering from anxiety or depression.

Related Reading: cymbalta | anxiety | indigestion

Comment from: LeahR 19-24 Female less than 1 month Patient Published: August 10

Gave me severe muscle spasms and made me even more nauseated.

Related Reading: muscle spasms

Comment from: Elizabethsomething 25-34 Female less than 1 month Patient Published: July 19

This is the most horrendous drug Iâ??ve ever had in my body. I went to the ER 3 nights ago for a debilitating migraine and received the â??headache cocktailâ? injections, one of which was Reglan. I was completely out of it from the other two medicines they gave me, so my symptoms presented the next morning. Muscle issues in my jaw and limbs, nausea and vomiting, diarrhea, shaking and twitching, internal tremors, the worst is the major state of panic Iâ??ve been in for 3 days now. If Iâ??m not having a complete meltdown, Iâ??m in the verge of a panic attack while my heart beats out of my chest. I feel trapped in my body and have to urge to just scream for hours. My doctor told me today to keep taking diphenhydramine to counteract the Reglan until itâ??s effects are gone in another day or two so thatâ??s my only option unfortunately. This drug should not exist and the â??rareâ? side effects seem anything but rare after looking into user reviews. Itâ??s a dopamine antagonist and is a danger to people. If you must take it, please be so very cautious and take the warnings with careful consideration. Especially if you have any existing anxiety or depression. I was desperate at the ER and didn't even question the drugs I was receiving. I will never do that again. And I will NEVER take this medication for as long as I live. I wouldnâ??t wish it on my worst enemy!

Related Reading: headache | reglan | nausea and vomiting

Comment from: Jd 45-54 Female less than 1 month Patient Published: April 07

After vomiting everything I eat and drink for 8 weeks treats I was hospitalized and many tests were run. I was unable to get through the gastric emptying study because I could not keep the nuclear egg sandwich down. So they thought I might have gastroparesis and had me take this medicine one time. One time was all I could do because it instantly made it hard for me to breathe and gave me a horrific headache. I was extremely dizzy and confused. I will never take it again and they have put it on my allergy list.

Related Reading: gastroparesis | headache | allergy

Comment from: 55-64 Female less than 1 month Patient Published: January 05

Only took this med for two days. At night had weird dreams,restlessness, could not sleep at all. Having suicidal thoughts, very paranoid. Couldn't wait for it to wear off. Had trembling and anxiety problems. Read reviews terrible drug not going to take it. This drug should come with a high warning and be banned.

Related Reading: anxiety

Comment from: Geeee 35-44 Female 5 to less than 10 years Patient Published: November 22

I was prescribed to take three times a day for nausea and no motility for a Transthoracic Esophagectomy after Cancer. I take ONLY one 10mg dose a day as needed. Works great!

Related Reading: cancer

Comment from: Felicia81 35-44 Female 1 to less than 2 years Patient Published: November 20

I have been taking Reglan 5mg, 4x daily, for about 1 and half year's. My doctor watches me very close. None of my other meds react with it. I'm on anti depressant, anxiety meds, nerve blockers, and bipolar meds. I was very aware of the bad side effects, but I have gastropresis and the pain was so bad I felt like I was dying. But with Reglan, and my other meds I'm finally feeling human. I do get tremors and I knew it could happen. But I'm living better on Reglan and having to take all the meds then I would have without it. Its a hard decision but I'm better off with it.

Related Reading: reglan | anxiety | tremors

Comment from: Retired 65-74 Female 1 to 6 months Patient Published: August 09

I was having problems with reflux. I couldnâ??t sleep at night because of the burning in my throat. The doctor prescribed Reglan 4 x daily. Took it for 2 1/2 months. I noticed that I would start crying during tv shows, commercials, etc. my body felt shaky and tingly inside but there was no shakiness on the outside of my body. I couldnâ??t sleep and I didnâ??t care if I talked to anyone. All I wanted to do was stay by myself. I was taking care of my infant grandson, and after being on the Reglan for 2 months, I dreaded taking care of him. Before the meds, I was looked forward each day to taking care of him. I finally looked at the prescription information, and it said the medication could cause severe depression in women over 50. That was so true! This happened in the spring of 2009. Itâ??s been over 9 years now, and once in a while, Iâ??ll have that feeling like I was going to have a panic attack or a feeling of depression. This medication has been one of the worse medicines I have ever taken. I will NEVER take it again. In my opinion, it shouldnâ??t ever be prescribed. I talked to my OBY/GYN about what happened, and she was very adamant about me never taking it again. She said it could cause severe depression in women. She couldnâ??t believe my PCP had prescribed it for me.

Related Reading: reglan | depression

Comment from: judy 65-74 Male 6 months to less than 1 year Patient Published: February 10

Do not use this drug in any form, I used the generic and had a year of my life stolen from me. Spent much of the time in deep depression, anxiety, shaking, facial grimace and had to go on two different meds to get me through this nightmare This drug is banned in Europe and Canada and should be taken off the market here in USA. I wrote FDA numerous times, no response, Black box warning now a little too late.

Related Reading: depression | anxiety

Comment from: tecmerc 45-54 Male 6 months to less than 1 year Patient Published: February 01

suicidal ideation,try like a hot knife to your brain. horrible, painful, terrifying. Paranoid ideation. I have a fast brain, just fill in what my life was like. lost one job, almost lost another. This drug should be your very last choice, it almost was mine. I told my doctor about it, he wrote in the soap notes "makes patient extremely tired". Did my first sentences relay that fact? I don't think so. Obfuscation is unseemly in a physician. I know there aren't many or any good choices but seriously, tell the poor guy who's nearly starving to death that this drug may very well push him over the edge. It nearly ended me, be very careful. Stomach motility eventually returned and I am starting to gain weight. The journey was dark and terrible. I am not sure I could do it again. As the drug leaves my system the ideations are gone and the lingering side effect is sleeplessness.


Digestive Disorders: Common Misconceptions See Slideshow
Comment from: 25-34 Female less than 1 month Patient Published: November 13

I was very worried about the symptoms and or reactions it can cause. I have a great team of gastro doctors who are following my gastro paresis as it is pretty bad. This medication has helped tremendously and its been only 2 weeks.

Comment from: TMalave 45-54 Female 1 to 6 months Patient Published: July 26

I am on Oral Reglan 3x day - 5mg each time. I've been on the oral for roughly 4-6 weeks. I am suffering from severe muscle spasms in my right eye and my arms and legs are so spasmatic with muscle cramps and pain. I can't keep still, I fidget all the time and sleep - I can't get comfortable and toss and turn and flip all night long. I find myself just standing instead of sitting for long periods of time. I'm so jittery and hyped up from this med. I haven't felt like this ever and I am so miserable and in so much pain. I wouldn't recommend this drug to anyone!

Related Reading: reglan | muscle spasms | muscle cramps

Comment from: Fix Me 55-64 Female 1 to 6 months Patient Published: May 20

I am a diabetic and have been having trouble with nausea and vomiting for more than a year, my stomach always feels full. I was started on this drug and finally in over a year, I can eat and not be full, no more nausea. I even know what its like to feel hungry again. My doctor recommend I stop it. I did and within 24 hours I was back to square one. I started taking it again and I feel great. Thank goodness for this pill.

Related Reading: nausea and vomiting

Comment from: Ems33 25-34 Female less than 1 month Patient Published: March 19

I was given this by my doctor to help my milk supply and so fat it is great and I feel great and it's doing it's job.

Comment from: Dumbfounded 55-64 Female 2 to less than 5 years Patient Published: September 23

I was given Reglan for my gastroparesis for over four years. This was years ago. Was not informed of the terrible side affects. Depression, anxiety, tremors, restlessness, you name it I had it. Doctors thought it was all psychological. After all of these years every once in a while the side affects show up. The doctors were not informed back then to slowly remove the medicine. Now I take Domperidone. Works wonderfully. Have been taking it for years. Why the FDA will not take Reglan off the market and approve Domperidone is beyond me. FYI - If you take Domperidone and are ever in the hospital for a period of time the hospital may not approve your use of Domperidone while in the hospital. I had complications after surgery. Suffered constantly with my gastroparesis.

Related Reading: reglan | gastroparesis | depression

Comment from: jj 35-44 Female 2 to less than 5 years Caregiver Published: May 11

Horrible side effects. Parkinson's -type movements and tardive dyskinesia, as well as depression. We are told it will likely never resolve. Avoid this drug as possible.

Related Reading: tardive dyskinesia | depression

Comment from: SD FLATLANDER 65-74 Female less than 1 month Patient Published: April 13

Imust be allergic to it. I have the bulk of the sde effects, insomnia, agitation, dizziness, unsteady on my feet, difficulty speaking clearly, headaches, could not control mybladder (peed my pants), irritability. Nasty stuff for me.

Related Reading: insomnia | dizziness


Medical Editor: John P. Cunha, DO, FACOEP

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