Comment from: Bella 55-64 Transgender 1 to 6 months Caregiver Published: July 24

The application is extremely difficult. The bottle is impossible for arthritic hands to squeeze out. I ended up wasting 25% from the 3 bottles I tried and will not be renewing the Rx. I did not notice any improvement in my extreme dry eye issue. Very frustrating.

Comment from: SGS 55-64 Transgender less than 1 month Caregiver Published: June 26

I used Restasis for 15 days. Initially I experienced burning and redness in my eyes, but as the days passed the side effects increased. By day 10 I was experiencing substantial pain in the joints of my knees, hips, shoulders, and elbows. By day 12 I began experiencing pain in my lower back and right side. On day 14 I could not stand up and stayed in bed all day due to the excruciating pain in my lower back and side. On day 15 I started researching side effects and quit taking this drug. In addition to these symptoms I also experienced diarrhea, severe dry mouth, bags under my eyes, darkened urine, a stabbing pain in my right ear, heart palpitations, elevated blood pressure, heavy sinus congestion and a feeling of smothering when I was lying down due to substantial mucus buildup in my sinus cavities and throat. During this time the only thing in my life that had changed was starting the use of Restasis. I read the Restasis literature for side effects and realized that some of my symptoms fell under the 'contact your doctor immediately if you experience these symptoms' category. I called my eye doctor on day 15 to report what I was experiencing and was told that none of my symptoms were related to Restasis (despite my assertion that they are listed in Restasis' own side-effects literature). Today is day 19. After being off of Restasis for 4 days the pain in my lower back and right side has diminished only slightly. I am able to walk with assistance. Joint pain is still present, as are the sinus problems, diarrhea, and a slightly lessened occurrence of heart palpitations. After reading pages and pages of self-reported very similar side effects of this drug, with symptoms resolving after discontinuing use, it is my hope that within a week without using Restasis my symptoms will dissipate. It is my absolute belief that all of my symptoms described above are attributable to my use of Restasis.

Related Reading: restasis | diarrhea | dry mouth

Comment from: Uncle Gar 75 or over Transgender less than 1 month Caregiver Published: June 18

Very costly Rx. Very little results. I don't see (no pun) any difference.

Comment from: Billie 75 or over Transgender less than 1 month Caregiver Published: June 12

You need to at least put this in a bottle and not a vial. The vial is hard to use and I lose drops. It is to expensive to have such a cheap container that can hurt your eye. It seems more drops are wasted than used. I can't afford to toss this out, but will not be using it again when this runs out. Very disappointed!

Comment from: 45-54 Female 2 to less than 5 years Patient Published: April 11

Worst eye drop bottle ever. Please make them easier to use!!!!! And not so wasteful!!!!

Comment from: WhatsGoinOn 55-64 Female 1 to 6 months Patient Published: March 11

I have the individual daily dose droppers. It seems to have helped. However, I wonder if the Restasis "My Tears, My Rewards" program is a farce. Because Express Scripts won't deal with manufacturer coupons, I have to submit claims to the My Rewards program. I submitted 1/26/2021. Called and I was told a check was issued 2/23/2021. It is now 3/11/2021 and the check has not arrived.

Related Reading: restasis

Comment from: bjh1159 55-64 Female less than 1 month Patient Published: February 13

I have to stop using this medication after only the second dose. When I have an allergic reaction to ANY medication, I usually feel it in my eyes first. After only the second dose of Restasis my eyes became dangerously swollen and the whites of my eyes were completely red and painful. So, I'm going to take that as a sign that I am allergic to this stuff. Now I have over $1,800 worth (retail) of a medication I can't, and won't use.

Related Reading: restasis

Comment from: 65-74 Female 6 months to less than 1 year Patient Published: December 09

While the drops help , it is disgraceful that this company advertises that â??if you cannot pay for this Restasis may helpâ?.....unless you are a Senior citizen who is on Medicare .... we are the people who need the drops.... donâ??t expect your hollow advertisement to make a difference...disgusting

Related Reading: restasis

Comment from: Nivea 35-44 Female 1 to less than 2 years Patient Published: June 02

Everything was fine until .. Until I realized I am losing hair and have Alopecia :( .. but the damage was done and now I am trying to fix my Alopecia .

Comment from: NA 55-64 Male less than 1 month Patient Published: February 22

Burning eyes

Comment from: Cheryl 55-64 Female 1 to 6 months Patient Published: January 27

Medication burns for an hour or more after use, sometimes so badly I can not see. (I do refrigerate it as my Dr suggested.) My vision is more blurry and my eyes feel more 'gritty' than when I began 2 months ago. It seems I have a constant, slightly sore throat. I am only 63 but have osteoarthritis in my hands - this has truly been worse and I did not believe it was from Restasis. I know it must be because I have been Gluten free to help the arthritis. This medication was suppose to help my severely dry eyes - it has made them worse! Sad there is no help for dry eyes. This drug is not the answer.

Related Reading: burns | sore throat | osteoarthritis

Comment from: 65-74 Female 6 months to less than 1 year Patient Published: December 02

Restasis made my dry eye feel worse and eyes were always red , itchy, and watery. This product is very expensive and does not work for everyone. I used it for 6 months and stopped using it a week ago and for the first time in 6 months my eyes are no longer red, itchy and watery. I use Gen Teal jel and warm compress and I my eyes feel so much better. I would not recommend this product!

Related Reading: restasis

Comment from: 45-54 Female 1 to 6 months Patient Published: November 20

I am a Registered Nurse with no known medical conditions. Since taking Restasis I have had swimmer's ear, chronic neck and back pain and have openly said to my family "I feel like I am having an arthritis flare" (the problem is that I do not have arthritis). Although I was getting the drug FOR FREE with a manufacturer coupon I am stopping this drug today.

Related Reading: restasis | swimmer's ear | arthritis

Comment from: 75 or over Female 10 years or more Patient Published: May 02

The plastic bottle is so hard that I cannot get the drops out with my arthritic fingers. I would rather have the files but my pharmacy only has the bottles. My eye doctors will have to prescribe something else.

Comment from: skd 1218 45-54 Female 2 to less than 5 years Patient Published: May 01

This medication seems to help my dry eyes. The vials are a pain - but I prefer them to the multi use bottle. The bottle is very hard to get drops out of and then you get more than one drop at a time. And the bottle doesnâ??t even last 30 days yet itâ??s same cost as double the amount of vials.

Related Reading: dry eyes

Comment from: Yole 65-74 Female less than 1 month Patient Published: April 24

I used for 3 days. For 2 days, I used every 12 hours. The 3rd day I used only once. I stopped because my chest felt tight and had a feeling like the start of a chest cold.My throat got real dry and as of now still have globus sensation (2 1\2 weeks later). My arms got soar but don't think it was from Restasis.

Related Reading: restasis

Comment from: americanjosh19 35-44 Male less than 1 month Patient Published: March 20

I was prescribed this but could only stand to use it for 2 weeks. It makes my eyes feel so much drier and very gritty. The solution, in this case, is worse than the problem. I couldn't try it long enough to see if it would eventually be effective. A side note - those who say that the eye drops impact your immune system please note that this is likely not true. The amount of drop that enters your body is very minimal and the concentration of drug that enters your bloodstream would be even less. It is a localized application of a tiny amount of the drug. When used orally or via injection the same drug, in much higher and concentrated dosage, does work to suppress your immune system.


What causes dry eyes? See Answer
Comment from: jlfoster7 55-64 Female 6 months to less than 1 year Patient Published: February 16

Although Restasis vials were easy to use and recap for multiple use, my severe dry eye and corneal scarring continued. I was using high quality drops during the day and gel at night in addition to Restasis. My eyes became red, irritated, and painful after about 8 months of use. This week I learned I have ocular lymphoma (a form of non-Hodgkin's lymphoma) and am being worked up to see if it has spread. From literature research I've learned Restasis can suppress certain cells in the immune system to cause cancers to form. The longer you're on it, and depending partly on your genetic makeup, the higher your risk. The drug company needs to acknowledge this, but can't unless those who have the disease report it.

Related Reading: restasis

Comment from: Nou 25-34 Female less than 1 month Patient Published: February 12

Useless, expensive, and dried my eyes even more.. I regret listening to my dr. About it.


Medical Editor: John P. Cunha, DO, FACOEP

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