Simulect

Last updated on RxList: 11/15/2021
Simulect Patient Information Including Side Effects

Brand Names: Simulect

Generic Name: basiliximab

What is basiliximab (Simulect)?

Basiliximab is used with other medications to prevent organ rejection after a kidney transplant. Basiliximab weakens your immune system to prevent your body from "rejecting" the transplanted kidney.

Basiliximab may also be used for purposes not listed in this medication guide.

What are the possible side effects of basiliximab (Simulect)?

Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching; feeling like you might pass out; sneezing, wheezing, difficult breathing; fast heartbeats; swelling of your face, lips, tongue, or throat.

An allergic reaction may occur up to 24 hours after a basiliximab injection.

Call your doctor at once if you have:

  • trouble breathing;
  • pain or burning when you urinate;
  • joint pain, redness, or stiffness;
  • a surgical wound that will not heal;
  • easy bruising, unusual bleeding, purple or red spots under your skin;
  • swelling in your hands or feet;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor;
  • high blood potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;
  • low blood potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;
  • low red blood cells (anemia)--pale skin, tiredness, feeling light-headed or short of breath, cold hands and feet; or
  • signs of infection--fever, chills, sore throat, body aches, unusual tiredness, vomiting, diarrhea.

Common side effects may include:

  • stomach pain or upset, nausea, vomiting;
  • diarrhea, constipation;
  • cold symptoms such as stuffy nose, sore throat;
  • headache;
  • increased blood pressure;
  • tremors;
  • sleep problems (insomnia);
  • acne; or
  • swelling in your hands, ankles, or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about basiliximab (Simulect)?

You may get infections or bleed more easily. Call your doctor if you have unusual bleeding or signs of infection (fever, cough, skin sores, painful urination).

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Simulect Patient Information including How Should I Take

What should I discuss with my healthcare provider before receiving basiliximab (Simulect)?

You should not use basiliximab if you are allergic to it.

Tell your doctor if you have ever had:

May harm an unborn baby. Use effective birth control while receiving basiliximab and for at least 4 months after your last dose. Tell your doctor if you become pregnant.

Do not breastfeed.

How is basiliximab given (Simulect)?

Basiliximab is injected into a vein by a healthcare provider.

This medicine must be given slowly over 30 minutes.

Basiliximab is usually given just before your transplant and again 4 days afterward.

You may get infections or bleed more easily. You will need medical tests.

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Simulect Patient Information including If I Miss a Dose

What happens if I miss a dose (Simulect)?

In a medical setting you are not likely to miss a dose.

What happens if I overdose (Simulect)?

In a medical setting an overdose would be treated quickly.

What should I avoid while receiving basiliximab (Simulect)?

Avoid receiving a "live" vaccine, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles). Ask your doctor how soon after treatment you can safely receive a live vaccine.

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

What other drugs will affect basiliximab (Simulect)?

Other drugs may affect basiliximab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information (Simulect)?

Your doctor or pharmacist can provide more information about basiliximab.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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