Singulair vs. Advair

Are Singulair and Advair the Same Thing?

Singulair (montelukast) and Advair HFA (salmeterol and fluticasone) are used to treat asthma.

Singulair is also used to treat and allergic rhinitis and to prevent exercise-induced narrowing of the airways.

Advair HFA is also used to treat chronic bronchitis.

Advair HFA (salmeterol and fluticasone) contains a combination of a corticosteroid and a beta2-adrenergic bronchodilator used for treating asthma and chronic bronchitis.

Singulair and Advair HFA belong to different drug classes. Singulair is a leukotriene receptor and Advair HFA is a combination of a corticosteroid and a beta2-adrenergic bronchodilator.

What Are Possible Side Effects of Singulair?

Common side effects of Singulair include:

What Are Possible Side Effects of Advair?

Common side effects of Advair include:

  • upper respiratory tract infections,
  • headaches,
  • dizziness,
  • nausea,
  • vomiting,
  • stomach upset,
  • diarrhea,
  • yeast infections of the mouth or throat (oral thrush),
  • sore throat,
  • dry mouth/nose/throat,
  • stuffy nose,
  • sinus pain,
  • cough,
  • sore throat,
  • hoarseness or deepened voice, and
  • musculoskeletal pain.

What Is Singulair?

Singulair (montelukast) is a leukotriene receptor antagonist drug used in the treatment of asthma and allergic rhinitis. Singulair is also indicated for prevention of exercise-induced narrowing of the airways.

What Is Advair?

Advair Diskus (fluticasone and salmeterol oral inhaler) is a combination of a corticosteroid and a beta2-adrenergic bronchodilator used to treat asthma and chronic bronchitis, including COPD associated with chronic bronchitis. Advair Diskus is used in patients whose symptoms are not adequately controlled on a long-term asthma control medication, since one of the active ingredients in salmeterol is LABA, which has been linked to asthma-related deaths. Advair Diskus should not be used to treat acute episodes of asthma or COPD. Advair Diskus is available in generic form.

What Drugs Interact With Singulair?

Singulair may interact with phenobarbital or rifampin

What Drugs Interact With Advair?

Advair may interact with amiodarone, diuretics (water pills), HIV medicines, MAO inhibitors, antidepressants, antibiotics, or beta-blockers

How Should Singulair Be Taken?

The following doses of Singulair are recommended: For adults and adolescents 15 years of age and older: one 10-mg tablet. For pediatric patients 6 to 14 years of age: one 5-mg chewable tablet. For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg oral granules. For pediatric patients 12 to 23 months of age: one packet of 4-mg oral granules. Singulair may interact with phenobarbital or rifampin.

How Should Advair Be Taken?

For patients aged 12 years and older, the dosage of Advair Diskus is 1 inhalation twice daily, approximately 12 hours apart.


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RxList. Singulair Side Effects Drug Center.
RxList. Advair Side Effects Drug Center.

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