Skelaxin

Last reviewed on RxList: 7/30/2020
Skelaxin Side Effects Center

Pharmacy Editor: Eni Williams, PharmD, PhD

What Is Skelaxin?

Skelaxin (metaxalone) is a skeletal muscle relaxant prescribed for the short-term treatment of painful muscle spasms. Skelaxin is available as a generic drug.

What Are Side Effects of Skelaxin?

Common side effects of Skelaxin include:

Tell your doctor if you experience serious side effects of Skelaxin including stomach pain, loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).

Dosage for Skelaxin

Skelaxin usual dose is 800 mg taken three or four times daily.

What Drugs, Substances, or Supplements Interact with Skelaxin?

Significant drug interactions have not been reported with Skelaxin although it may increase the sedative effects of alcohol and drugs that cause sedation.

Skelaxin During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant during treatment with Skelaxin; it may harm a fetus. It is unknown if Skelaxin passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Additional Information

Our Skelaxin Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. articles.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Skelaxin Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using metaxalone and call your doctor at once if you have:

  • weak or shallow breathing;
  • a light-headed feeling, like you might pass out;
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness; or
  • upper stomach pain, loss of appetite, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • dizziness, drowsiness;
  • nausea, vomiting, upset stomach;
  • headache; or
  • feeling nervous or irritable;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Skelaxin (Metaxalone)

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Skelaxin Professional Information

SIDE EFFECTS

The most frequent reactions to metaxalone include:

CNS: drowsiness, dizziness, headache, and nervousness or “irritability”;

Digestive: nausea, vomiting, gastrointestinal upset.

Other adverse reactions are:

Immune System: hypersensitivity reaction, rash with or without pruritus;

Hematologic: leukopenia; hemolytic anemia;

Hepatobiliary: jaundice.

Though rare, anaphylactoid reactions have been reported with metaxalone.

Read the entire FDA prescribing information for Skelaxin (Metaxalone)

© Skelaxin Patient Information is supplied by Cerner Multum, Inc. and Skelaxin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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