Skyrizi vs. Taltz

Are Skyrizi and Taltz the Same Thing?

Skyrizi (risankizumab-rzaa) and Taltz (ixekizumab) are used to treat moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.

Skyrizi and Taltz are interleukin antagonists that target different proteins. Skyrizi is an interleukin-23 antagonist and Cosentyx is an interleukin-17A antagonist.

Side effects of Skyrizi and Taltz that are similar include upper respiratory infections (runny or stuffy nose, rhinovirus infections), injection site reactions (bruising, redness, fluid leakage, bleeding, infection, inflammation, irritation, pain, itching, swelling, warmth), and tinea infections (such as ringworm, athlete's foot, and jock itch).

Side effects of Skyrizi that are different from Taltz include headache and fatigue.

Side effects of Taltz that are different from Skyrizi include nausea.

Both Skyrizi and Taltz may interact with “live” vaccines.

Taltz may also interact with warfarin and cyclosporine.

What Are Possible Side Effects of Skyrizi?

Side effects of Skyrizi include:

  • upper respiratory infections,
  • headache,
  • fatigue,
  • injection site reactions (bruising, redness, fluid leakage, bleeding, infection, inflammation, irritation, pain, itching, swelling, warmth), and
  • tinea infections (such as ringworm, athlete's foot and jock itch)

What Are Possible Side Effects of Taltz?

Common side effects of Taltz include:

  • injection site reactions (redness, pain)
  • upper respiratory tract infections (runny or stuffy nose, rhinovirus infections)
  • nausea, and
  • fungal infections (ringworm, athlete's foot and jock itch)

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow

What Is Skyrizi?

Skyrizi (risankizumab-rzaa) is an interleukin-23 antagonist indicated for the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.

What Is Taltz?

Taltz (ixekizumab) injection is a humanized interleukin-17A antagonist indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

What Drugs Interact With Skyrizi?

Skyrizi may interact with "live" vaccines. Tell your doctor all medications and supplements you use and all vaccines you recently received. Tell your doctor if you are pregnant or plan to become pregnant before using Skyrizi; it is unknown how it would affect a fetus. It is unknown if Skyrizi passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Taltz?

Taltz may interact with "live" vaccines, warfarin, and cyclosporine. Tell your doctor all medications and supplements you use and all vaccines you recently received.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer

How Should Skyrizi Be Taken?

The dose of Skyrizi is 150 mg (two 75 mg injections) administered by subcutaneous injection at Week 0, Week 4 and every 12 weeks thereafter.

How Should Taltz Be Taken?

The recommended dose of Taltz is 160 mg (two 80 mg injections) at Week 0, followed by 80 mg at Weeks 2, 4, 6, 8, 10, and 12, then 80 mg every 4 weeks.

Disclaimer

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References
SOURCE:

AbbVie Inc. Skyrizi Product Information.
https://www.skyrizi.com
Eli Lilly and Company. Taltz Product Information.
www.taltz.com/?

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