Slo-phyllin Side Effects Center

Last updated on RxList: 7/26/2022
Slo-phyllin Side Effects Center

What Is Slo-Phyllin?

Slo-Phyllin (theophylline tablets) is a bronchodilator used for relief and/or prevention of symptoms of asthma and reversible bronchospasm associated with chronic bronchitis and emphysema. The brand name Slo-Phyllin is discontinued, but generic versions may be available.

What Are Side Effects of Slo-Phyllin?

Common side effects of Slo-Phyllin (theophylline tablets) include:

  • nausea,
  • vomiting,
  • abdominal discomfort,
  • headache,
  • insomnia,
  • diarrhea,
  • irritability,
  • restlessness,
  • muscle tremors,
  • increased urination,
  • decreased blood pressure, and
  • heart palpitations

Slo-Phyllin may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • severe or continued vomiting,
  • ongoing headache,
  • trouble sleeping,
  • rapid heartbeats,
  • seizure,
  • fever,
  • leg cramps,
  • constipation,
  • irregular heartbeats,
  • fluttering in your chest,
  • numbness or tingling,
  • muscle weakness,
  • limp feeling,
  • increased thirst,
  • increased urination,
  • dry mouth, and
  • fruity breath odor

Get medical help right away, if you have any of the symptoms listed above.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Slo-Phyllin

The initial dose of Slo-Phyllin is 16 mg/kg/24 hours or 400 mg/24 hours (whichever is less) of anhydrous theophylline in divided doses at 6-or 8-hour intervals.

What Drugs, Substances, or Supplements Interact with Slo-Phyllin?

Slo-Phyllin may interact with ephedrine, or other sympathomimetic bronchodilators. Tell your doctor all medications and supplements you use.

Slo-Phyllin During Pregnancy or Breastfeeding

During pregnancy, Slo-Phyllin should be used only if prescribed. This drug passes into breast milk and may cause irritability or other signs of mild toxicity in nursing infants. Consult your doctor before breastfeeding.

Additional Information

Our Slo-Phyllin (theophylline tablets) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Slo-phyllin Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe or continued vomiting;
  • ongoing headache, trouble sleeping;
  • rapid heartbeats;
  • a seizure;
  • new signs of illness (especially fever);
  • low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; or
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor.

Serious side effects may be more likely in older adults.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • headache;
  • sleep problems (insomnia);
  • tremors;
  • sweating; or
  • feeling restless or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Slo-phyllin (Theophylline, Anhydrous)

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
Slo-phyllin Professional Information

SIDE EFFECTS

The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency. The most consistent adverse reactions are usually due to overdosage.

Gastrointestinal: nausea, vomiting, epigastric pain, hematemesis, diarrhea.

Central Nervous System: headaches, irritability, restlessness, insomnia, reflex hyperexcitability, muscle twitching, clonic and tonic generalized convulsions.

Cardiovascular: palpitation, tachycardia, extrasystoles, flushing, hypotension, circulatory failure, ventricular arrhythmias.

Respiratory: tachypnea.

Renal: potentiation of diuresis.

Other: alopecia, hyperglycemia, inappropriate ADH syndrome, rash.

Read the entire FDA prescribing information for Slo-phyllin (Theophylline, Anhydrous)

© Slo-phyllin Patient Information is supplied by Cerner Multum, Inc. and Slo-phyllin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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