- Are Solu-Medrol and Prednisone the Same Thing?
- How Should Prednisone Be Taken?
- What Are Possible Side Effects of Solu-Medrol?
- What Are Possible Side Effects of Prednisone?
- What Is Solu-Medrol?
- What Is Prednisone?
- What Drugs Interact With Solu-Medrol?
- What Drugs Interact With Prednisone?
- How Should Solu-Medrol Be Taken?
- How Should Prednisone Be Taken?
Are Solu-Medrol and Prednisone the Same Thing?
Solu-Medrol (methylprednisolone) and prednisone are corticosteroids used for severe or incapacitating allergic conditions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, rheumatic disorders, and several other conditions.
- Side effects of Solu-Medrol and prednisone that are similar include weight gain, headache, thinning and easy bruising of the skin, nausea, vomiting, trouble sleeping, and acne.
- Side effects of Solu-Medrol that are different from prednisone include fluid retention, high blood pressure, potassium loss, muscle weakness, puffiness of the face, hair growth on the face, glaucoma, cataracts, peptic ulcers, high blood sugar (hyperglycemia), irregular menstrual periods, growth retardation in children, convulsions, heartburn, dizziness, appetite changes, increased sweating, psychiatric disturbances, and injection site reactions (pain, redness, or swelling).
- Side effects of prednisone that are different from Solu-Medrol include restlessness.
- Both Solu-Medrol and prednisone may interact with live or inactivated vaccines, potassium-depleting agents (e.g., amphotericin B, diuretics), antidiabetic drugs, estrogens (including oral contraceptives), anticoagulants, azole antifungals, and rifampin.
- Solu-Medrol may also interact with erythromycin.
- Prednisone may also interact with macrolide antibiotics, anticholinesterase, isoniazid, bupropion, cholestyramine, cyclosporine, digitalis glycosides, fluoroquinolones, barbiturates, seizure medications, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), quetiapine, skin tests, and thalidomide.
- Some conditions may worsen or you may experience withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness) when Solu-Medrol or prednisone are suddenly stopped.
How Should Prednisone Be Taken?
What Are Possible Side Effects of Solu-Medrol?
Common side effects of Solu-Medrol include:
- fluid retention,
- weight gain,
- high blood pressure,
- potassium loss,
- muscle weakness,
- puffiness of the face,
- hair growth on the face,
- thinning and easy bruising of the skin,
- peptic ulcers,
- high blood sugar (hyperglycemia),
- irregular menstrual periods,
- growth retardation in children,
- trouble sleeping,
- appetite changes,
- increased sweating,
- psychiatric disturbances, and
- injection site reactions (pain, redness, or swelling).
What Are Possible Side Effects of Prednisone?
Common side effects of Prednisone include:
- acne, thinning skin,
- weight gain,
- restlessness, and
- trouble sleeping.
Tell your doctor if you experience serious side effects of prednisone including
- severe allergic reactions (skin rash, itching, hives, swelling of your lips/face/tongue),
- mood changes or depression,
- eye pain or vision changes,
- sore throat,
- difficulty urinating, or
- high blood sugar (increased thirst, increased urination, confusion, or swelling of the ankles and feet).
What Is Solu-Medrol?
What Is Prednisone?
What Drugs Interact With Solu-Medrol?
What Drugs Interact With Prednisone?
Prednisone may also interact with antibiotics, anticholinesterase, isoniazid, bupropion, cholestyramine, cyclosporine, digitalis glycosides, estrogens (including oral contraceptives), barbiturates, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), quetiapine, skin tests, thalidomide, and live or inactivated vaccines.
Following prolonged therapy, withdrawal of corticosteroids such as dexamethasone or prednisone may result in symptoms of the corticosteroid withdrawal syndrome including muscle or joint pain and feeling unwell (malaise).
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FDA. Prednisone Product Information.