Sotradecol

Last updated on RxList: 2/1/2018
Sotradecol Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/01/2018

Sotradecol (sodium tetradecyl sulfate) Injection is a sclerosing agent used to treat small, uncomplicated varicose veins in the legs. Sotradecol is not a cure for varicose veins and the effects of this medication may not be permanent. Common side effects of Sotradecol include:

  • mild headache
  • nausea
  • vomiting
  • discolored skin along the treated vein (may be permanent)
  • injection site reactions (pain, hives, ulveration), or
  • allergic reactions (hives, hay fever, asthma, and severe anaphylaxis)

The strength of solution of Sotradecol required depends on the size and degree of varicosity. In general, a dose using the 1% solution will be found most useful with the 3% solution preferred for larger varicosities. Sotradecol may interact with birth control pills or other medications that stop or prevent ovulation (ovaries releasing eggs). Tell your doctor all medications and supplements you use. During pregnancy, Sotradecol should be used only if prescribed. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our Sotradecol (sodium tetradecyl sulfate) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Sotradecol Consumer Information

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; sneezing, runny nose, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pain or swelling in one or both legs;
  • chest pain, sudden cough, wheezing, rapid breathing, fast heart rate; or
  • pain, itching, peeling, skin sores, or skin changes where the medicine was injected.

Common side effects may include:

  • mild headache;
  • nausea, vomiting; or
  • discolored skin along the treated vein (may be permanent).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Sotradecol (Sodium Tetradecyl)

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Sotradecol Professional Information

SIDE EFFECTS

Local reactions consisting of pain, urticaria or ulceration may occur at the site of injection. A permanent discoloration may remain along the path of the sclerosed vein segment. Sloughing and necrosis of tissue may occur following extravasation of the drug. (See WARNINGS section).

Allergic reactions such as hives, asthma, hay fever and anaphylactic shock have been reported. Mild systemic reactions that have been reported include headache, nausea and vomiting. (See WARNINGS section).

At least six deaths have been reported with the use of Sotradecol® (sodium tetradecyl) . Four cases of anaphylactic shock leading to death have been reported in patients who received Sotradecol® (sodium tetradecyl) . One of these four patients reported a history of asthma, a contraindication to the administration of Sotradecol®. (See WARNINGS section).

One death has been reported in a patient who received Sotradecol® (sodium tetradecyl) and who had been receiving an an ovulatory agent. Another death (fatal pulmonary embolism) has been reported in a 36-year-old female treated with sodium tetradecyl acetate and who was not taking oral contraceptives.

Read the entire FDA prescribing information for Sotradecol (Sodium Tetradecyl)

© Sotradecol Patient Information is supplied by Cerner Multum, Inc. and Sotradecol Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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