Definition of Southern tick-associated rash illness

Reviewed on 3/29/2021

Southern tick-associated rash illness: A disease characterized by a rash like that in Lyme disease, recognized in the southeastern and south-central US, associated with the bite of the lone star tick, Amblyomma americanum. The tick transmits the agent of the disease, a spirochete named Borrelia lonestari. The rash is red and expands with central clearing (the rash of erythema migrans). Treatment is with antibiotics.


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