- Muscle pain and stiffness should be reported to
the doctor immediately as these could be a sign of muscle damage.
- Blood testing
is also required to detect any liver damage.
- Lipitor should be used with caution
in patients with alcohol or other liver diseases.
- Other minor side effects include constipation, diarrhea, fatigue, gas, heartburn, and headache.
Lipitor is generally well-tolerated, and side effects are rare. However, like all medications, it requires monitoring for side effects. Among the side effects that are routinely monitored:
A peculiar cross reaction with a specific food exists with Lipitor and other "statin" drugs used to lower cholesterol. Grapefruit juice blocks special enzymes in the wall of the small intestine that actually destroy many medications, including Lipitor, and prevents their absorption into the body. Thus, in the normal state, smaller amounts of the drugs get into the body than are ingested. When the action of these enzymes is blocked (as by grapefruit juice), more of the drugs get into the body, and the blood levels of these medications increase. This can lead to toxic side effects from Lipitor, such as liver or muscle damage.
So beware of this unusual direct link to a medication hazard with Lipitor when choosing breakfast beverages!
Robert J. Bryg, MD
Board Certified Internal Medicine with subspecialty in Cardiovascular Disease