- Are Streptase and Activase the Same Thing?
- What Are Possible Side Effects of Streptase?
- What Are Possible Side Effects of Activase?
- What Is Streptase?
- What Is Activase?
- What Drugs Interact with Streptase?
- What Drugs Interact with Activase?
- How Should Streptase Be Taken?
- How Should Activase Be Taken?
Are Streptase and Activase the Same Thing?
Streptase (streptokinase) and Activase (alteplase) are enzymes used in the treatment of heart attack or lung blood clots (pulmonary embolism) as well as leg blood clots (deep venous thrombosis-DVT).
The brand name drug Streptase is no longer available in the U.S. Generic forms may be available.
Side effects of Streptase and Activase that are similar include nausea, dizziness, low blood pressure (hypotension), mild fever, bleeding (including gastrointestinal bleeding, genitourinary bleeding, bruising, nosebleed, and bleeding gums), and allergic reactions (swelling, rash, hives).
Side effects of Streptase that are different from Activase include headache, rash, itching, flushing, muscle or bone pain, shivering, and nerve damage.
Side effects of Activase that are different from Streptase include vomiting.
Both Streptase and Activase may interact with blood thinners, nonsteroidal anti-inflammatory drugs (NSAIDs), or aspirin.
What Are Possible Side Effects of Streptase?
Common side effects of Streptase include:
- low blood pressure,
- mild fever,
- bleeding from wounds or gums,
- muscle or bone pain,
- shivering, and
- allergic reactions.
Streptase can also cause nerve damage.
What Are Possible Side Effects of Activase?
Common side effects of Activase include:
- The most common side effect of Activase is bleeding, including gastrointestinal bleeding, genitourinary bleeding, bruising, nosebleed, and bleeding gums. Other side effects of Activase include:
- low blood pressure (hypotension),
- mild fever, or
- allergic reactions (swelling, rash, hives).
What Is Streptase?
Streptase (streptokinase) is an enzyme used in the treatment of heart attack or lung blood clots (pulmonary embolism) as well as leg blood clots (deep venous thrombosis-DVT). The brand name drug Streptase is no longer available in the U.S. Generic versions may be available.
What Is Activase?
Activase (alteplase) is an enzyme, which works to break up and dissolve blood clots that can block arteries, used in the treatment of an acute heart attack or pulmonary embolism.
What Drugs Interact With Streptase?
Streptase may interact with blood thinners, non-steroidal anti-inflammatory drugs (NSAIDs), or aspirin. Drugs that can reverse effects of streptokinase include aminocaproic acid, aprotinin, and tranexamic acid. Tell your doctor all medications you are taking.
What Drugs Interact With Activase?
Activase may interact with blood thinners, or aspirin. Tell your doctor all medications and supplements you use. During pregnancy, Activase should be used only if prescribed. It is unknown if this drug is passes into breast milk. Consult your doctor before breastfeeding.
How Should Streptase Be Taken?
Streptase (streptokinase) is given by injection by a health care professional. Dose is dependent upon the condition of the patient and response to treatment.
How Should Activase Be Taken?
The recommended total dose of Activase is based upon patient weight, not to exceed 100 mg.
Health Solutions From Our Sponsors
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).
Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.
If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
Medscape. Streptase Drug Information.
Genentech. Activase Product Monograph.