Definition of Subacute Sclerosing Panencephalitis (SSPE)

Reviewed on 9/29/2022

Subacute sclerosing panencephalitis (SSPE) is a chronic brain disease of children and adolescents that occurs months to often years after an attack of measles, causing convulsions, motor abnormalities, mental retardation, and usually, death.


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.

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