Other Name(s):

Acide d'Ambre, Acide Butanedioïque, Acide Éthylène Dicarboxylique, Acide Succinique, Amber, Amber Acid, Ammonium Succinate, Butanedioic Acid, Esprit Volatil de Succin, Oil of Amber, Sel Volatil de Succin, Spirit of Amber, Succinato, Succinic Acid, Succinum.


Succinate or succinic acid is involved in several chemical processes in the body. In supplements, it is used for symptoms related to menopause such as hot flashes and irritability.

Succinate is also applied to the skin for arthritis and joint pain.

How does it work?

It is not known how succinate might work for any medical condition.


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Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Symptoms of menopause.
  • Arthritis.
  • Pain.
More evidence is needed to rate succinate for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

There is not enough information to know if succinate is safe.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough information to know if succinate is safe during pregnancy and breast-feeding. It should be avoided.


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The appropriate dose of succinate depends on several factors such as the user's age, health, and several other conditions. At this time, there is not enough scientific information to determine an appropriate range of doses for succinate. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Peskov AB, Maevskii EI, Uchitel ML, et al. Succinate-based preparation alleviates manifestations of the climacteric syndrome in women. Bull Exp Biol Med 2005;140:312-4. View abstract.

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