Sultrin Side Effects Center

Last updated on RxList: 8/16/2022
Sultrin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Sultrin?

Sultrin (sulfathiazole, sulfacetamide and sulfabenzamide) Cream is a topical antibacterial preparation used to treat vaginitis caused by Haemophilus (Gardnerella) vaginalis bacteria. The brand name Sultrin Cream is discontinued, but generic versions may be available.

What Are Side Effects of Sultrin?

Common side effects of Sultrin (sulfathiazole, sulfacetamide and sulfabenzamide) Cream include:

  • localized irritation
  • burning
  • itching
  • an increased need to urinate, or
  • allergy

Sultrin may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • severe dizziness,
  • itching,
  • burning,
  • skin rash,
  • redness or swelling of the skin,
  • burning at the application site, and
  • rash or irritation of the penis of sexual partner

Get medical help right away, if you have any of the symptoms listed above.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Sultrin

The dose of Sultrin is one full applicator intravaginally twice daily for four to six days.

What Drugs, Substances, or Supplements Interact with Sultrin?

Sultrin may interact with other drugs. Tell your doctor all medications and supplements you use.

Sultrin During Pregnancy or Breastfeeding

During pregnancy, Sultrin should be used only if prescribed. Because of the potential for serious adverse reactions in nursing infants, breastfeeding is not recommended while using this drug.

Additional Information

Our Sultrin (sulfathiazole, sulfacetamide and sulfabenzamide) Cream Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Sultrin Professional Information


There has been one reported case of Agranulocyctosis in a patient receiving SULTRIN (sulfathiazole, sulfacetamide and sulfabenzamide) Cream. The most frequent adverse reactions to SULTRIN (sulfathiazole, sulfacetamide and sulfabenzamide) are localized irritation and/or allergy including rare reports of Stevens-Johnson syndrome which may be fatal.

Read the entire FDA prescribing information for Sultrin (Sulfathiazole, Sulfacetamide and Sulfabenzamide)


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© Sultrin Patient Information is supplied by Cerner Multum, Inc. and Sultrin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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